Bioisosterism:  A Rational Approach in Drug Design

Patani and LaVoie provide an overview of bioisosteres. Bioisosteres modulate biological activity by virtue of subtle differences in their physiochemical properties.

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Bibliographic Details
Published in:Chemical reviews 1996-12, Vol.96 (8), p.3147-3176
Main Authors: Patani, George A, LaVoie, Edmond J
Format: Article
Language:English
Subjects:
Biochemistry
Pharmaceuticals
Pharmacology
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Description
Summary:Patani and LaVoie provide an overview of bioisosteres. Bioisosteres modulate biological activity by virtue of subtle differences in their physiochemical properties.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr950066q