Imaging findings in faciobrachial dystonic seizures associated with LGI-1 antibodies

A 76-year-old woman presented with a three-month history of faciobrachial dystonic seizures associated with cognitive impairment and hyponatremia. Cerebrospinal fluid analysis was unremarkable. A whole-body CT scan demonstrated no malignancies. Brain MRI revealed involvement of the mesial right temp...

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Bibliographic Details
Published in:Arquivos de neuro-psiquiatria 2016-11, Vol.74 (11), p.947-947
Main Authors: Grativvol, Ronnyson Susano, Simabukuro, Mateus Mistieri, Spera, Raphael Ribeiro, Cavalcante, Wagner Cid Palmeira, Araújo, Hugo Henrique Soares, Sakuno, Daniel, Lucato, Leandro Tavares, Pinto, Lécio Figueira, Castro, Luiz Henrique Martins, Nitrini, Ricardo
Format: Article
Language:English
Subjects:
Aged
Cognitive Dysfunction - complications
Dystonic Disorders - complications
Dystonic Disorders - diagnostic imaging
Female
Humans
IMAGES IN NEUROLOGY
Magnetic Resonance Imaging
Proteins - immunology
Seizures - diagnostic imaging
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Summary:A 76-year-old woman presented with a three-month history of faciobrachial dystonic seizures associated with cognitive impairment and hyponatremia. Cerebrospinal fluid analysis was unremarkable. A whole-body CT scan demonstrated no malignancies. Brain MRI revealed involvement of the mesial right temporal lobe, right striatum and globus pallidus and bilateral supratentorial white matter (Figures A, B, C). Leucine-rich glioma inactivated protein 1 (LGI-1) antibodies were detected in the serum.
ISSN:0004-282X
1678-4227
1678-4227
0004-282X
DOI:10.1590/0004-282X20160146