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Cutaneous carcinosarcoma: a series of six cases and a review of the literature
Background Cutaneous carcinosarcoma is a rare tumor with distinct malignant epithelial and mesenchymal cell populations. The histologic subtypes of epithelial and mesenchymal components in cutaneous carcinosarcoma are variable, as an assortment of carcinomatous and sarcomatous patterns have been des...
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Published in: | Journal of cutaneous pathology 2017-01, Vol.44 (1), p.34-44 |
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Main Authors: | , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Background
Cutaneous carcinosarcoma is a rare tumor with distinct malignant epithelial and mesenchymal cell populations. The histologic subtypes of epithelial and mesenchymal components in cutaneous carcinosarcoma are variable, as an assortment of carcinomatous and sarcomatous patterns have been described in the literature.
Methods
Clinical information was obtained from patient charts and archival slides were retrieved and reviewed.
Results
We present a novel series of six distinct cases of cutaneous carcinosarcoma and review the literature. Our cases consisted of basal cell, pilomatrical, squamous cell, and trichoblastic variants. These cases occurred in elderly men on sun exposed skin with treatment and follow up was available for 4 of 6 cases. The four cases were treated with Mohs micrographic surgery with mean follow up of nine months.
Conclusion
We report six cases of cutaneous carcinosarcoma with distinctive clinical and histologic characterization not previously described in a single series. |
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ISSN: | 0303-6987 1600-0560 |
DOI: | 10.1111/cup.12843 |