A cross-sectional evaluation of the correlation between disease severity and quality of life in chronic rhinosinusitis patients in Nigeria

Quality of Life (QoL) studies are increasingly being used as the primary outcome measure in chronic rhinosinusitis (CRS) globally. However, little is known about QoL and the interplay of identifiable factors on QoL in CRS in sub-Saharan Africa. This study investigated the correlation between disease...

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Bibliographic Details
Published in:European archives of oto-rhino-laryngology 2015-09, Vol.272 (9), p.2341-2346
Main Authors: Olowosusi, O. Z., Asoegwu, C. N., Olagunju, A. T., Nwawolo, C. C.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Chronic Disease
Cross-Sectional Studies
Female
Head and Neck Surgery
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Neurosurgery
Nigeria
Otorhinolaryngology
Quality of Life
Rhinitis - psychology
Rhinology
Severity of Illness Index
Sinusitis - psychology
Young Adult
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Summary:Quality of Life (QoL) studies are increasingly being used as the primary outcome measure in chronic rhinosinusitis (CRS) globally. However, little is known about QoL and the interplay of identifiable factors on QoL in CRS in sub-Saharan Africa. This study investigated the correlation between disease severity and QoL in chronic rhinosinusitis patients. A total of 147 adults with subjective severity rating of CRS were studied. Participants were assessed using designed questionnaire, Individual Rhinosinusitis Symptom Severity Score Assessment (IRSSSA) and Rhinosinusitis Disability Index (RSDI) questionnaires to elicit socio-demographic/clinical profile, CRS symptom severity and QoL, respectively. The mean age of the participants was 36.86 ± 11.91 years. The mean severity score of all 147 CRS cases was 3.8 ± 1.13. The majority of participants ( N  = 80; 54.4 %) had moderate disease. The RSDI mean scores for the participants for overall HRQoL were 40.6 ± 19.8. (Median = 40; Range = 77), for physical domain 15.2 ± 7.7, functional domain 12.1 ± 6.4 and emotional domain 13.2 ± 8.2. The trend of association between the disease severity scores and the overall HRQoL on Pearson linear correlation indicates a positive linear association of worsening overall HRQoL with increasing disease severity ( R  = 0.83; P  
ISSN:0937-4477
1434-4726
DOI:10.1007/s00405-014-3348-0