Reactive oxygen species (ROS) and cancer: role of antioxidative nutraceuticals

Highlights • ROS has complex role in different stages of cancer development. • ROS involves in transformation, tumor survival, proliferation, invasion and metastasis of cancer cells. • Consumption of antioxidant nutraceuticals may reduce the incidence as well as helpful in treatment of cancer.

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Bibliographic Details
Published in:Cancer letters 2017-02, Vol.387, p.95-105
Main Authors: Prasad, Sahdeo, Gupta, Subash C, Tyagi, Amit K
Format: Article
Language:English
Subjects:
Animals
Antioxidant
Antioxidants
Antioxidants - therapeutic use
Cadmium
Cancer
Cell cycle
Deoxyribonucleic acid
Dietary Supplements
DNA
Ethanol
Gene expression
Hematology, Oncology and Palliative Medicine
Humans
Hypoxia
Kinases
Nanoparticles
Neoplasms - drug therapy
Neoplasms - metabolism
Nutraceuticals
Oxidative Stress - drug effects
Oxygen
Physiology
Proteins
Reactive Oxygen Species - metabolism
ROS
Transcription factors
Tumorigenesis
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Description
Summary:Highlights • ROS has complex role in different stages of cancer development. • ROS involves in transformation, tumor survival, proliferation, invasion and metastasis of cancer cells. • Consumption of antioxidant nutraceuticals may reduce the incidence as well as helpful in treatment of cancer.
ISSN:0304-3835
1872-7980
DOI:10.1016/j.canlet.2016.03.042