Simultaneous CT angiography and whole-body CT is an effective imaging approach before multiorgan retrieval

Abstract Purpose To assess the role of whole-body computed tomography (CT) for determining morphological suitability before multiorgan retrieval (MOR) in brain dead patients. Materials and methods Fifty-one clinically brain dead patients (21 women, 30 men; mean age 61 year ± 15) were included in thi...

Full description

Saved in:
Bibliographic Details
Published in:Diagnostic and interventional imaging 2017-03, Vol.98 (3), p.235-243
Main Authors: Berthier, E, Ridereau-Zins, C, Dubé, L, Tchouante, P, Nedelcu, C, Lasocki, S, Aubé, C
Format: Article
Language:English
Subjects:
Brain Death
Computed tomography
Computed Tomography Angiography
Donor Selection - methods
Donor selection. Multiorgan retrieval
Female
Humans
Male
Middle Aged
Organ donation
Prospective Studies
Radiology
Tissue and Organ Harvesting
Tissue Donors
Tomography, X-Ray Computed
Whole Body Imaging
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Purpose To assess the role of whole-body computed tomography (CT) for determining morphological suitability before multiorgan retrieval (MOR) in brain dead patients. Materials and methods Fifty-one clinically brain dead patients (21 women, 30 men; mean age 61 year ± 15) were included in this prospective, single center study. All patients had CT angiography of the brain and whole-body CT examination. CT images were evaluated for the presence of morphological abnormalities of lungs, liver and other abdominal organs and presence of vascular anatomical variants. The results of CT examinations were compared to intraoperative findings observed during organ harvesting and/or the results of histopathological analysis of biopsy specimens. The impact of whole-body CT examination on the harvesting process was evaluated. Results Ninety-five percent of vascular anatomical variants that were found intraoperatively were depicted on CT. CT density measurements predicted surgical finding of steatosis in 80% of patients. Whole-body CT changed the MOR strategy in 21/51 patients (41%) including 3 MOR cancellations and 8 grafts refusals, whereas organ harvesting was continued in 10 patients after histopathological analysis was performed. Conclusion Selection of potential graft donors using whole-body CT is reliable and improves graft selection during MOR.
ISSN:2211-5684
2211-5684
DOI:10.1016/j.diii.2016.05.012