Breast cancer and thyroid diseases: analysis of 867 consecutive cases

• Published in: Journal of endocrinological investigation 2017-02, Vol.40 (2), p.179-184
• Main Authors: Chiappa, C., Rovera, F., Rausei, S., Del Ferraro, S., Fachinetti, A., Lavazza, M., Marchionini, V., Arlant, V., Tanda, M. L., Piantanida, E., Kim, H. Y., Anuwong, A., Dionigi, G.
• Format: Article
• Language: English
• Subjects: Autoimmunity; Biomarkers, Tumor - metabolism; Breast cancer; Breast Neoplasms - etiology; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Carcinoma, Ductal, Breast - etiology; Carcinoma, Ductal, Breast - metabolism; Carcinoma, Ductal, Breast - secondary; Carcinoma, Lobular - etiology; Carcinoma, Lobular - metabolism; Carcinoma, Lobular - secondary; Endocrinology; Female; Follow-Up Studies; Humans; Lymph nodes; Lymphatic Metastasis; Male; Medicine; Medicine & Public Health; Metabolic Diseases; Middle Aged; Neoplasm Grading; Original Article; p53 Protein; Prognosis; Receptors, Estrogen - metabolism; Receptors, Progesterone - metabolism; Signal transduction; Thyroid Diseases - complications; Tumors
• ISSN: 1720-8386; 0391-4097; 1720-8386
• DOI: 10.1007/s40618-016-0543-4

Introduction The aim of this study was to evaluate the association of breast cancer with thyroid diseases. Many authors have already studied the possible relationship between these two diseases, but the results are nowadays conflicting. Materials and methods Our study examining 867 patients with breast cancer (862 women and 5 men, average age = 61 years old) of whom 141 also had thyroid disease evaluated the recurrence of thyroid diseases and their association with different types of breast cancer. Statistical analyses were performed using SPSS software for Windows; we used nonparametric tests (Chi-square and Mann–Whitney), and the level of significance was set at p