Methods of Fat Tissue Processing for Human Vocal Fold Injection: A Systematic Review

Summary Objectives We analyzed different methods used to process autologous fat tissues for vocal fold injection (VFI). VFI is a safe procedure that preserves the folds' original elasticity and vibration properties and rarely triggers foreign-body reactions, but is often a temporary treatment d...

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Bibliographic Details
Published in:Journal of voice 2017-03, Vol.31 (2), p.244.e17-244.e21
Main Authors: Truzzi, Giselle M, Pauna, Henrique F, Bette, Patricia, Gusmão, Reinaldo J, Crespo, Agrício N, Semenzati, Graziela O
Format: Article
Language:English
Subjects:
Acoustics
Adipose Tissue - transplantation
Elasticity
Humans
Injections
Laryngoplasty - adverse effects
Laryngoplasty - methods
Lipectomy - adverse effects
Otolaryngology
Recovery of Function
Speech Acoustics
Time Factors
Tissue and Organ Harvesting - adverse effects
Tissue and Organ Harvesting - methods
Transplantation, Autologous
Treatment Outcome
Vibration
Vocal Cords - physiopathology
Vocal Cords - surgery
Voice Disorders - diagnosis
Voice Disorders - physiopathology
Voice Disorders - surgery
Voice Quality
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Summary:Summary Objectives We analyzed different methods used to process autologous fat tissues for vocal fold injection (VFI). VFI is a safe procedure that preserves the folds' original elasticity and vibration properties and rarely triggers foreign-body reactions, but is often a temporary treatment due to fat reabsorption. To avoid it, selecting a technique that provides as many viable implantable adipocytes as possible is mandatory. Study Design This is a systematic review. Methods Data were collected from PubMed, Embase, Ovid, and Cochrane Library. Authors systematically reviewed databases for papers on autologous fat tissue processing methods involving human injections in vocal folds and vocalization outcomes that evolved the acoustic analysis of the voice before and after the surgical procedure, independently of the follow-up time. Results Nine out of the 517 articles met selection criteria for analysis. No standardized technique was found. Conclusion There is no standardized technique for processing fat tissue for vocal fold injection. Further research is needed to point out the best available technique.
ISSN:0892-1997
1873-4588
DOI:10.1016/j.jvoice.2016.08.012