Effectiveness Assessment When Pharmacokinetics Makes A Difference, Macrolides And Azalide Example

PK characteristics of azithromycin provides high tissue concentrations. Since the majority of bacterial infections in humans are tissue based (with the exception of blood and cerebrospinal liquid infections) tissue concentrations of antimicrobials are of foremost importance for the treatment outcome...

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Bibliographic Details
Published in:Clinical therapeutics 2016-10, Vol.38 (10), p.e8-e9
Main Author: Francetic, I
Format: Article
Language:English
Subjects:
Antimicrobial agents
Internal Medicine
Medical Education
Plasma
Online Access:Get full text
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Summary:PK characteristics of azithromycin provides high tissue concentrations. Since the majority of bacterial infections in humans are tissue based (with the exception of blood and cerebrospinal liquid infections) tissue concentrations of antimicrobials are of foremost importance for the treatment outcome.
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2016.07.104