Loading…

Inflammatory Bowel Disease: Joint Management in Gastroenterology and Dermatology

Inflammatory bowel disease (IBD) is a complex entity that includes Crohn disease and ulcerative colitis. It is characterized by a chronic proinflammatory state of varying intensity that often leads to considerable morbidity. In the last decade, several therapeutic targets have been identified that a...

Full description

Saved in:
Bibliographic Details
Published in:Actas dermo-sifiliográficas (English ed.) 2017-04, Vol.108 (3), p.184-191
Main Authors: Sánchez-Martínez, M A, Garcia-Planella, E, Laiz, A, Puig, L
Format: Article
Language:eng ; spa
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Inflammatory bowel disease (IBD) is a complex entity that includes Crohn disease and ulcerative colitis. It is characterized by a chronic proinflammatory state of varying intensity that often leads to considerable morbidity. In the last decade, several therapeutic targets have been identified that are susceptible to the use of biological agents, including anti-tumor necrosis factor alpha antibodies, which are associated with paradoxical psoriasiform reactions in 5% of patients. Decision-making in the management of these cases requires close collaboration between the dermatologist and gastroenterologist. Inflammatory bowel disease is also associated with various other dermatologic and rheumatologic manifestations, and presents a genetic and pathogenic association with psoriasis that justifies both the interdisciplinary approach to these patients and the present review.
ISSN:1578-2190
DOI:10.1016/j.ad.2016.07.007