Bendiocarb induced histopathological and biochemical alterations in rat liver and Preventive role of vitamins C and E

Highlights • Effects of bendiocarp on liver were studied in rats. • Bendiocarp treatment increased the antioxidant enzyme of oxidative stress biomarkers. • Bendiocarp treatment caused several histopathological changes in rats. • Vitamins C and E protect liver tissues.

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Bibliographic Details
Published in:Environmental toxicology and pharmacology 2017-01, Vol.49, p.148-155
Main Authors: Apaydin, Fatma Gökçe, Baş, Hatice, Kalender, Suna, Kalender, Yusuf
Format: Article
Language:English
Subjects:
Animals
Antioxidants
Antioxidants - pharmacology
Ascorbic acid
Ascorbic Acid - pharmacology
Bendiocarb
Body weight
Catalase - metabolism
Emergency
Enzymatic activity
Glutathione Peroxidase - metabolism
Glutathione Transferase - metabolism
Histopathology
Insecticides - toxicity
Lipid peroxidation
Lipid Peroxidation - drug effects
Liver
Liver - drug effects
Liver - pathology
Liver toxicity
Male
Malondialdehyde
Oxidative stress
Parameters
Peroxidation
Phenylcarbamates - toxicity
Rats, Wistar
Rodents
Statistical analysis
Studies
Superoxide Dismutase - metabolism
Tocopherol
Toxicity
Vitamin C
Vitamin E
Vitamin E - pharmacology
Vitamins
Vitamins - pharmacology
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Description
Summary:Highlights • Effects of bendiocarp on liver were studied in rats. • Bendiocarp treatment increased the antioxidant enzyme of oxidative stress biomarkers. • Bendiocarp treatment caused several histopathological changes in rats. • Vitamins C and E protect liver tissues.
ISSN:1382-6689
1872-7077
DOI:10.1016/j.etap.2016.11.018