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A conjugate Lewis base-Brønsted acid catalyst for the sulfenylation of nitrogen containing heterocycles under mild conditions

Catalysts that contain a thiourea tethered to a carboxylic acid were found to affect the sulfenylation of indoles and other N-heterocycles on the hour time scale at room temperature. The mild nature of these conditions allowed for the incorporation of diverse functionalities into more complex hetero...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2017, Vol.53 (9), p.1494-1497
Main Authors: Nalbandian, Christopher J, Miller, Eric M, Toenjes, Sean T, Gustafson, Jeffery L
Format: Article
Language:English
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Summary:Catalysts that contain a thiourea tethered to a carboxylic acid were found to affect the sulfenylation of indoles and other N-heterocycles on the hour time scale at room temperature. The mild nature of these conditions allowed for the incorporation of diverse functionalities into more complex heterocycles.
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc09998j