Loading…

Proteomic Study of Blood Serum in Coronary Atherosclerosis

Changes in the blood serum proteins were assessed in men with coronary atherosclerosis and without coronary heart disease. Proteins were separated by 2D-electrophoresis, protein fractions were identified by their peptide fingerprint by MALDI method; fractions with more than twofold increase in prote...

Full description

Saved in:
Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2017, Vol.162 (3), p.343-345
Main Authors: Stakhneva, E. M., Meshcheryakova, I. A., Demidov, E. A., Starostin, K. V., Ragino, Yu. I., Peltek, S. E., Voevoda, M. I.
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c470t-8e7a076fa3766cfe58b9747fd5474b615d0312588357c0ba568292ea3bc10f613
cites cdi_FETCH-LOGICAL-c470t-8e7a076fa3766cfe58b9747fd5474b615d0312588357c0ba568292ea3bc10f613
container_end_page 345
container_issue 3
container_start_page 343
container_title Bulletin of experimental biology and medicine
container_volume 162
creator Stakhneva, E. M.
Meshcheryakova, I. A.
Demidov, E. A.
Starostin, K. V.
Ragino, Yu. I.
Peltek, S. E.
Voevoda, M. I.
description Changes in the blood serum proteins were assessed in men with coronary atherosclerosis and without coronary heart disease. Proteins were separated by 2D-electrophoresis, protein fractions were identified by their peptide fingerprint by MALDI method; fractions with more than twofold increase in protein level were determined. In blood serum of patients with coronary atherosclerosis, the content of C4 complement protein increased and ceruloplasmin level decreased, which is typical of heart failure and coronary heart disease.
doi_str_mv 10.1007/s10517-017-3611-7
format article
fullrecord <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1861537517</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A498583202</galeid><sourcerecordid>A498583202</sourcerecordid><originalsourceid>FETCH-LOGICAL-c470t-8e7a076fa3766cfe58b9747fd5474b615d0312588357c0ba568292ea3bc10f613</originalsourceid><addsrcrecordid>eNp1kdFL3TAUxsNQ5p3uD9jLKAiyl7qcpGnSvV0vcxMEheueQ5qeeCtt45L2wf9-KdfpVZSQhCS_85HzfYR8AXoKlMrvEagAmdM0eQmQyw9kAULyXDEGe2RBE5QXSqkD8inGu_lIS_hIDpiiFaiqWpAf18GP6PvWZutxah4y77KzzvsmW2OY-qwdspUPfjDhIVuOGww-2m5e23hE9p3pIn5-3A_Jn_OfN6vf-eXVr4vV8jK3haRjrlAaKktnuCxL61CoupKFdI0oZFGXIBrKgQmluJCW1kaUilUMDa8tUFcCPyTftrr3wf-dMI66b6PFrjMD-ilqUEmEy-REQo9foXd-CkP63UwJNnuhnqlb06FuB-fHYOwsqpdFpYTijLJEnb5BpdFgcssP6Np0_6LgZKdgg6YbN9F309j6Ib4EYQva5GMM6PR9aPvksAaq52D1NlidgtVzsHru7OtjZ1PdY_NU8T_JBLAtENPTcIthp_V3Vf8ByY6o1A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1865248888</pqid></control><display><type>article</type><title>Proteomic Study of Blood Serum in Coronary Atherosclerosis</title><source>Springer Link</source><creator>Stakhneva, E. M. ; Meshcheryakova, I. A. ; Demidov, E. A. ; Starostin, K. V. ; Ragino, Yu. I. ; Peltek, S. E. ; Voevoda, M. I.</creator><creatorcontrib>Stakhneva, E. M. ; Meshcheryakova, I. A. ; Demidov, E. A. ; Starostin, K. V. ; Ragino, Yu. I. ; Peltek, S. E. ; Voevoda, M. I.</creatorcontrib><description>Changes in the blood serum proteins were assessed in men with coronary atherosclerosis and without coronary heart disease. Proteins were separated by 2D-electrophoresis, protein fractions were identified by their peptide fingerprint by MALDI method; fractions with more than twofold increase in protein level were determined. In blood serum of patients with coronary atherosclerosis, the content of C4 complement protein increased and ceruloplasmin level decreased, which is typical of heart failure and coronary heart disease.</description><identifier>ISSN: 0007-4888</identifier><identifier>EISSN: 1573-8221</identifier><identifier>DOI: 10.1007/s10517-017-3611-7</identifier><identifier>PMID: 28091899</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adult ; Arteriosclerosis ; Atherosclerosis ; Biological products ; Biomedical and Life Sciences ; Biomedicine ; Blood ; Blood proteins ; Cardiac patients ; Cardiovascular disease ; Case-Control Studies ; Cell Biology ; Ceruloplasmin ; Ceruloplasmin - metabolism ; Commodity futures ; Complement C4 - metabolism ; Complement component C4 ; Coronary artery disease ; Coronary Artery Disease - blood ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - pathology ; Coronary heart disease ; Electrophoresis, Gel, Two-Dimensional ; Health risk assessment ; Heart diseases ; Heart failure ; Humans ; Internal Medicine ; Laboratory Medicine ; Male ; Mass spectrometry ; Middle Aged ; Pathology ; Proteins ; Proteomics - methods ; Serum proteins ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization</subject><ispartof>Bulletin of experimental biology and medicine, 2017, Vol.162 (3), p.343-345</ispartof><rights>Springer Science+Business Media New York 2017</rights><rights>COPYRIGHT 2017 Springer</rights><rights>Bulletin of Experimental Biology and Medicine is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-8e7a076fa3766cfe58b9747fd5474b615d0312588357c0ba568292ea3bc10f613</citedby><cites>FETCH-LOGICAL-c470t-8e7a076fa3766cfe58b9747fd5474b615d0312588357c0ba568292ea3bc10f613</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28091899$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stakhneva, E. M.</creatorcontrib><creatorcontrib>Meshcheryakova, I. A.</creatorcontrib><creatorcontrib>Demidov, E. A.</creatorcontrib><creatorcontrib>Starostin, K. V.</creatorcontrib><creatorcontrib>Ragino, Yu. I.</creatorcontrib><creatorcontrib>Peltek, S. E.</creatorcontrib><creatorcontrib>Voevoda, M. I.</creatorcontrib><title>Proteomic Study of Blood Serum in Coronary Atherosclerosis</title><title>Bulletin of experimental biology and medicine</title><addtitle>Bull Exp Biol Med</addtitle><addtitle>Bull Exp Biol Med</addtitle><description>Changes in the blood serum proteins were assessed in men with coronary atherosclerosis and without coronary heart disease. Proteins were separated by 2D-electrophoresis, protein fractions were identified by their peptide fingerprint by MALDI method; fractions with more than twofold increase in protein level were determined. In blood serum of patients with coronary atherosclerosis, the content of C4 complement protein increased and ceruloplasmin level decreased, which is typical of heart failure and coronary heart disease.</description><subject>Adult</subject><subject>Arteriosclerosis</subject><subject>Atherosclerosis</subject><subject>Biological products</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Blood</subject><subject>Blood proteins</subject><subject>Cardiac patients</subject><subject>Cardiovascular disease</subject><subject>Case-Control Studies</subject><subject>Cell Biology</subject><subject>Ceruloplasmin</subject><subject>Ceruloplasmin - metabolism</subject><subject>Commodity futures</subject><subject>Complement C4 - metabolism</subject><subject>Complement component C4</subject><subject>Coronary artery disease</subject><subject>Coronary Artery Disease - blood</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Coronary Artery Disease - pathology</subject><subject>Coronary heart disease</subject><subject>Electrophoresis, Gel, Two-Dimensional</subject><subject>Health risk assessment</subject><subject>Heart diseases</subject><subject>Heart failure</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Laboratory Medicine</subject><subject>Male</subject><subject>Mass spectrometry</subject><subject>Middle Aged</subject><subject>Pathology</subject><subject>Proteins</subject><subject>Proteomics - methods</subject><subject>Serum proteins</subject><subject>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp1kdFL3TAUxsNQ5p3uD9jLKAiyl7qcpGnSvV0vcxMEheueQ5qeeCtt45L2wf9-KdfpVZSQhCS_85HzfYR8AXoKlMrvEagAmdM0eQmQyw9kAULyXDEGe2RBE5QXSqkD8inGu_lIS_hIDpiiFaiqWpAf18GP6PvWZutxah4y77KzzvsmW2OY-qwdspUPfjDhIVuOGww-2m5e23hE9p3pIn5-3A_Jn_OfN6vf-eXVr4vV8jK3haRjrlAaKktnuCxL61CoupKFdI0oZFGXIBrKgQmluJCW1kaUilUMDa8tUFcCPyTftrr3wf-dMI66b6PFrjMD-ilqUEmEy-REQo9foXd-CkP63UwJNnuhnqlb06FuB-fHYOwsqpdFpYTijLJEnb5BpdFgcssP6Np0_6LgZKdgg6YbN9F309j6Ib4EYQva5GMM6PR9aPvksAaq52D1NlidgtVzsHru7OtjZ1PdY_NU8T_JBLAtENPTcIthp_V3Vf8ByY6o1A</recordid><startdate>2017</startdate><enddate>2017</enddate><creator>Stakhneva, E. M.</creator><creator>Meshcheryakova, I. A.</creator><creator>Demidov, E. A.</creator><creator>Starostin, K. V.</creator><creator>Ragino, Yu. I.</creator><creator>Peltek, S. E.</creator><creator>Voevoda, M. I.</creator><general>Springer US</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>2017</creationdate><title>Proteomic Study of Blood Serum in Coronary Atherosclerosis</title><author>Stakhneva, E. M. ; Meshcheryakova, I. A. ; Demidov, E. A. ; Starostin, K. V. ; Ragino, Yu. I. ; Peltek, S. E. ; Voevoda, M. I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-8e7a076fa3766cfe58b9747fd5474b615d0312588357c0ba568292ea3bc10f613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Arteriosclerosis</topic><topic>Atherosclerosis</topic><topic>Biological products</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Blood</topic><topic>Blood proteins</topic><topic>Cardiac patients</topic><topic>Cardiovascular disease</topic><topic>Case-Control Studies</topic><topic>Cell Biology</topic><topic>Ceruloplasmin</topic><topic>Ceruloplasmin - metabolism</topic><topic>Commodity futures</topic><topic>Complement C4 - metabolism</topic><topic>Complement component C4</topic><topic>Coronary artery disease</topic><topic>Coronary Artery Disease - blood</topic><topic>Coronary Artery Disease - diagnosis</topic><topic>Coronary Artery Disease - pathology</topic><topic>Coronary heart disease</topic><topic>Electrophoresis, Gel, Two-Dimensional</topic><topic>Health risk assessment</topic><topic>Heart diseases</topic><topic>Heart failure</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Laboratory Medicine</topic><topic>Male</topic><topic>Mass spectrometry</topic><topic>Middle Aged</topic><topic>Pathology</topic><topic>Proteins</topic><topic>Proteomics - methods</topic><topic>Serum proteins</topic><topic>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stakhneva, E. M.</creatorcontrib><creatorcontrib>Meshcheryakova, I. A.</creatorcontrib><creatorcontrib>Demidov, E. A.</creatorcontrib><creatorcontrib>Starostin, K. V.</creatorcontrib><creatorcontrib>Ragino, Yu. I.</creatorcontrib><creatorcontrib>Peltek, S. E.</creatorcontrib><creatorcontrib>Voevoda, M. I.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest_Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest Biological Science Journals</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Bulletin of experimental biology and medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stakhneva, E. M.</au><au>Meshcheryakova, I. A.</au><au>Demidov, E. A.</au><au>Starostin, K. V.</au><au>Ragino, Yu. I.</au><au>Peltek, S. E.</au><au>Voevoda, M. I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Proteomic Study of Blood Serum in Coronary Atherosclerosis</atitle><jtitle>Bulletin of experimental biology and medicine</jtitle><stitle>Bull Exp Biol Med</stitle><addtitle>Bull Exp Biol Med</addtitle><date>2017</date><risdate>2017</risdate><volume>162</volume><issue>3</issue><spage>343</spage><epage>345</epage><pages>343-345</pages><issn>0007-4888</issn><eissn>1573-8221</eissn><abstract>Changes in the blood serum proteins were assessed in men with coronary atherosclerosis and without coronary heart disease. Proteins were separated by 2D-electrophoresis, protein fractions were identified by their peptide fingerprint by MALDI method; fractions with more than twofold increase in protein level were determined. In blood serum of patients with coronary atherosclerosis, the content of C4 complement protein increased and ceruloplasmin level decreased, which is typical of heart failure and coronary heart disease.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>28091899</pmid><doi>10.1007/s10517-017-3611-7</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0007-4888
ispartof Bulletin of experimental biology and medicine, 2017, Vol.162 (3), p.343-345
issn 0007-4888
1573-8221
language eng
recordid cdi_proquest_miscellaneous_1861537517
source Springer Link
subjects Adult
Arteriosclerosis
Atherosclerosis
Biological products
Biomedical and Life Sciences
Biomedicine
Blood
Blood proteins
Cardiac patients
Cardiovascular disease
Case-Control Studies
Cell Biology
Ceruloplasmin
Ceruloplasmin - metabolism
Commodity futures
Complement C4 - metabolism
Complement component C4
Coronary artery disease
Coronary Artery Disease - blood
Coronary Artery Disease - diagnosis
Coronary Artery Disease - pathology
Coronary heart disease
Electrophoresis, Gel, Two-Dimensional
Health risk assessment
Heart diseases
Heart failure
Humans
Internal Medicine
Laboratory Medicine
Male
Mass spectrometry
Middle Aged
Pathology
Proteins
Proteomics - methods
Serum proteins
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
title Proteomic Study of Blood Serum in Coronary Atherosclerosis
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T13%3A18%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Proteomic%20Study%20of%20Blood%20Serum%20in%20Coronary%20Atherosclerosis&rft.jtitle=Bulletin%20of%20experimental%20biology%20and%20medicine&rft.au=Stakhneva,%20E.%20M.&rft.date=2017&rft.volume=162&rft.issue=3&rft.spage=343&rft.epage=345&rft.pages=343-345&rft.issn=0007-4888&rft.eissn=1573-8221&rft_id=info:doi/10.1007/s10517-017-3611-7&rft_dat=%3Cgale_proqu%3EA498583202%3C/gale_proqu%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c470t-8e7a076fa3766cfe58b9747fd5474b615d0312588357c0ba568292ea3bc10f613%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1865248888&rft_id=info:pmid/28091899&rft_galeid=A498583202&rfr_iscdi=true