The microRNA-449 family inhibits TGF-β-mediated liver cancer cell migration by targeting SOX4

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Bibliographic Details
Published in:Journal of hepatology 2017-05, Vol.66 (5), p.1012-1021
Main Authors: Sandbothe, Maria, Buurman, Reena, Reich, Nicole, Greiwe, Luisa, Vajen, Beate, Gürlevik, Engin, Schäffer, Vera, Eilers, Marlies, Kühnel, Florian, Vaquero, Alejandro, Longerich, Thomas, Roessler, Stephanie, Schirmacher, Peter, Manns, Michael P, Illig, Thomas, Schlegelberger, Brigitte, Skawran, Britta
Format: Article
Language:English
Subjects:
Acetylation
Animals
Carcinoma, Hepatocellular - pathology
Carcinoma, Hepatocellular - therapy
Cell migration
Cell Movement
Epigenetics
Gastroenterology and Hepatology
Genes, Tumor Suppressor - physiology
Histone acetylation
Histones - metabolism
Humans
Liver cancer
Liver Neoplasms - pathology
Liver Neoplasms - therapy
Metastasis
Mice
microRNA family
microRNA replacement therapy
MicroRNAs - physiology
SOXC Transcription Factors - genetics
Transforming Growth Factor beta - antagonists & inhibitors
Transforming Growth Factor beta - physiology
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Description
Summary:Graphical abstract
ISSN:0168-8278
1600-0641
DOI:10.1016/j.jhep.2017.01.004