Source of Ectopic ACTH Secretion Easily Identified by 68 Ga DOTANOC PET/CT

Malignant tumors account for most sources of ectopic ACTH Cushing syndrome (EA-CS). Early localization of the source and complete removal can be curative and also prevent metastasis. Diagnostic CT is known to perform better than PET/CT (low dose) in characterizing lung pathologies. However, bronchia...

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Bibliographic Details
Published in:Clinical nuclear medicine 2017-04, Vol.42 (4), p.295-296
Main Authors: Abubakar, Sofiullah, Amoako, Yaw Ampem, Kotze, Tessa, Tag, Naima
Format: Article
Language:English
Subjects:
ACTH Syndrome, Ectopic - diagnostic imaging
Bronchial Neoplasms - diagnostic imaging
Carcinoid Tumor - diagnostic imaging
Cushing Syndrome - diagnostic imaging
Female
Humans
Middle Aged
Organometallic Compounds
Positron Emission Tomography Computed Tomography
Radiopharmaceuticals
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Summary:Malignant tumors account for most sources of ectopic ACTH Cushing syndrome (EA-CS). Early localization of the source and complete removal can be curative and also prevent metastasis. Diagnostic CT is known to perform better than PET/CT (low dose) in characterizing lung pathologies. However, bronchial carcinoids, a common source of EA-CS, may be difficult to detect on chest CT scan especially when it is small and located close to the hilar region. We present a case of EA-CS due to bronchial carcinoid, which was easily seen on Ga DOTANOC PET/CT after a diagnostic chest CT was reported as normal.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000001541