Long-term Outcomes of Autologous Chondrocyte Implantation in Adolescent Patients

Background: Treating symptomatic articular cartilage lesions is challenging, especially in adolescent patients, because of longer life expectancies and higher levels of functional activity. For this population, long-term outcomes after autologous chondrocyte implantation (ACI) remain to be determine...

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Bibliographic Details
Published in:The American journal of sports medicine 2017-04, Vol.45 (5), p.1066-1074
Main Authors: Ogura, Takahiro, Bryant, Tim, Minas, Tom
Format: Article
Language:English
Subjects:
Adolescent
Cartilage
Cartilage, Articular - surgery
Chondrocytes - transplantation
Female
Follow-Up Studies
Humans
Knee
Knee Joint - surgery
Male
Orthopedic Procedures - methods
Pain - epidemiology
Pain Measurement
Periosteum - surgery
Sports medicine
Studies
Surveys and Questionnaires
Teenagers
Transplantation, Autologous
Transplants & implants
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Summary:Background: Treating symptomatic articular cartilage lesions is challenging, especially in adolescent patients, because of longer life expectancies and higher levels of functional activity. For this population, long-term outcomes after autologous chondrocyte implantation (ACI) remain to be determined. Purpose: To evaluate long-term outcomes in adolescents after ACI using survival analyses, validated outcome questionnaires, and standard radiographs. Study Design: Case series; Level of evidence, 4. Methods: We performed a review of prospectively collected data from patients who underwent ACI between 1996 and 2013. We evaluated 27 patients aged
ISSN:0363-5465
1552-3365
DOI:10.1177/0363546516682492