Synthetic Biology Takes on Zika

For the Zika diagnostic specifically (2), the first step is to release the RNA for detection through a simple boiling step at 95 °C for 2 min. Because Zika viral loads in saliva and serum are low-in the femtomole range-it is necessary to subsequently amplify material. [...]this proof of concept desi...

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Bibliographic Details
Published in:Clinical chemistry (Baltimore, Md.) Md.), 2017-02, Vol.63 (2), p.622-623
Main Authors: Kumar, Vikram Sheel, Webster, Molly
Format: Article
Language:English
Subjects:
Design
Genomes
Humans
Innovations
Laboratories
Public health
Sensors
Synthetic Biology
Vector-borne diseases
Zika virus
Zika Virus - metabolism
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Summary:For the Zika diagnostic specifically (2), the first step is to release the RNA for detection through a simple boiling step at 95 °C for 2 min. Because Zika viral loads in saliva and serum are low-in the femtomole range-it is necessary to subsequently amplify material. [...]this proof of concept design speaks to just how quickly teams might be able to address an outbreak-it took Collins' group just 6 weeks to bring this method to life.
ISSN:0009-9147
1530-8561
DOI:10.1373/clinchem.2016.269464