Polymorphisms in genes involved in enamel development are associated with dental fluorosis

Highlights • This study presents novel insights into the etiology of the dental fluorosis. • This study demonstrated that some polymorphisms in genes involved in the enamel development are associated with dental fluorosis. • It supports the role of genetic factors in different severities of dental f...

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Bibliographic Details
Published in:Archives of oral biology 2017-04, Vol.76, p.66-69
Main Authors: Küchler, Erika Calvano, Tannure, Patricia Nivoloni, Barroso de Oliveira, Daniela Silva, Charone, Senda, Nelson-Filho, Paulo, Bezerra da Silva, Raquel Assed, de Castro Costa, Marcelo, Antunes, Leonardo Santos, Calasans Maia, Mônica Diuana, Alves Antunes, Lívia Azeredo
Format: Article
Language:English
Subjects:
Adolescent
Advanced Basic Science
Alleles
Amelogenesis - genetics
Brazil
Child
Cross-Sectional Studies
Dental fluorosis
Dentistry
Female
Fluorosis, Dental - genetics
Gene
Genotype
Homeodomain Proteins - genetics
Humans
Male
Matrix Metalloproteinase 1 - genetics
Phenotype
Polymorphism
Polymorphism, Genetic
Real-Time Polymerase Chain Reaction
Tissue Inhibitor of Metalloproteinase-1 - genetics
Tissue Inhibitor of Metalloproteinase-2 - genetics
Transcription Factors - genetics
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Summary:Highlights • This study presents novel insights into the etiology of the dental fluorosis. • This study demonstrated that some polymorphisms in genes involved in the enamel development are associated with dental fluorosis. • It supports the role of genetic factors in different severities of dental fluorosis phenotypes.
ISSN:0003-9969
1879-1506
DOI:10.1016/j.archoralbio.2017.01.009