Salt metathesis for developing injectable supramolecular metallohydrogelators as a multi-drug-self-delivery system

Salt metathesis has been exploited to generate a series of non-steroidal anti-inflammatory drug (NSAID) based Zn(ii) metallohydrogels displaying both anti-inflammatory and anti-bacterial properties. Relatively low cytotoxicity, rheoreversibility and injectibility of one of these hydrogels make it su...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (95), p.13811-13814
Main Authors: Roy, Rajdip, Bhagyalalitha, Meduri, Choudhury, Pritam, Dastidar, Parthasarathi
Format: Article
Language:English
Subjects:
Antibacterial properties
Decomposition reactions
Hydrogels
Metathesis
Nonsteroidal antiinflammatory drugs
Toxicity
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Summary:Salt metathesis has been exploited to generate a series of non-steroidal anti-inflammatory drug (NSAID) based Zn(ii) metallohydrogels displaying both anti-inflammatory and anti-bacterial properties. Relatively low cytotoxicity, rheoreversibility and injectibility of one of these hydrogels make it suitable for multi-drug-self-delivery application.
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc07712a