Salt metathesis for developing injectable supramolecular metallohydrogelators as a multi-drug-self-delivery system

Salt metathesis has been exploited to generate a series of non-steroidal anti-inflammatory drug (NSAID) based Zn(ii) metallohydrogels displaying both anti-inflammatory and anti-bacterial properties. Relatively low cytotoxicity, rheoreversibility and injectibility of one of these hydrogels make it su...

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Published in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (95), p.13811-13814
Main Authors: Roy, Rajdip, Bhagyalalitha, Meduri, Choudhury, Pritam, Dastidar, Parthasarathi
Format: Article
Language:English
Subjects:
Antibacterial properties
Decomposition reactions
Hydrogels
Metathesis
Nonsteroidal antiinflammatory drugs
Toxicity
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cited_by cdi_FETCH-LOGICAL-c320t-d150b0a64cddc829e714f3592cb98b141ebfaee24c892f31b71687d6bbf102eb3
cites cdi_FETCH-LOGICAL-c320t-d150b0a64cddc829e714f3592cb98b141ebfaee24c892f31b71687d6bbf102eb3
container_end_page 13814
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creator Roy, Rajdip
Bhagyalalitha, Meduri
Choudhury, Pritam
Dastidar, Parthasarathi
description Salt metathesis has been exploited to generate a series of non-steroidal anti-inflammatory drug (NSAID) based Zn(ii) metallohydrogels displaying both anti-inflammatory and anti-bacterial properties. Relatively low cytotoxicity, rheoreversibility and injectibility of one of these hydrogels make it suitable for multi-drug-self-delivery application.
doi_str_mv 10.1039/c6cc07712a
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source Royal Society of Chemistry:Jisc Collections:Royal Society of Chemistry Read and Publish 2022-2024 (reading list)
subjects Antibacterial properties
Decomposition reactions
Hydrogels
Metathesis
Nonsteroidal antiinflammatory drugs
Toxicity
title Salt metathesis for developing injectable supramolecular metallohydrogelators as a multi-drug-self-delivery system
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