Multiresidue determination of 114 multiclass pesticides in flue-cured tobacco by solid-phase extraction coupled with gas chromatography and tandem mass spectrometry

A sensitive and robust multiresidue method for the simultaneous analysis of 114 pesticides in tobacco was developed based on solid‐phase extraction coupled with gas chromatography and tandem mass spectrometry. In this strategy, tobacco samples were extracted with acetonitrile and cleaned up with a m...

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Bibliographic Details
Published in:Journal of separation science 2016-12, Vol.39 (23), p.4629-4636
Main Authors: Cao, Jianmin, Sun, Na, Yu, Weisong, Pang, Xueli, Lin, Yingnan, Kong, Fanyu, Qiu, Jun
Format: Article
Language:English
Subjects:
Acetonitrile
Chromatography
Extraction
Gas chromatography
Gas chromatography with tandem mass spectrometry
Gas Chromatography-Mass Spectrometry
Mass spectrometry
Mathematical analysis
Multiresidue analysis
Nicotiana - chemistry
Pesticides
Pesticides - analysis
Scientific imaging
Solid Phase Extraction
Solids
Tandem Mass Spectrometry
Test procedures
Tobacco
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Summary:A sensitive and robust multiresidue method for the simultaneous analysis of 114 pesticides in tobacco was developed based on solid‐phase extraction coupled with gas chromatography and tandem mass spectrometry. In this strategy, tobacco samples were extracted with acetonitrile and cleaned up with a multilayer solid‐phase extraction cartridge Cleanert TPT using acetonitrile/toluene (3:1) as the elution solvent. Two internal standards of different polarity were used to meet simultaneous pesticides quantification demands in the tobacco matrix. Satisfactory linearity in the range of 10–500 ng/mL was obtained for all 114 pesticides with linear regression coefficients higher than 0.994. The limit of detection and limit of quantification values were 0.02–5.27 and 0.06–17.6 ng/g, respectively. For most of the pesticides, acceptable recoveries in the range of 70–120% and repeatabilities (relative standard deviation) of
ISSN:1615-9306
1615-9314
DOI:10.1002/jssc.201600914