Synthesis of hydrocinnamic esters by Pseudomonas cepacia lipase

Lipase from Pseudomonas cepacia was used to prepare esters of hydrocinnamic acid by direct esterification of the carboxylic acid in good yields (70–83%). For some esters, transesterification gave better yields (92%). Optimization of the reaction conditions resulted in a dramatic increase in the yiel...

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Bibliographic Details
Published in:Enzyme and microbial technology 2003-03, Vol.32 (3), p.485-490
Main Authors: Priya, K, Chadha, Anju
Format: Article
Language:English
Subjects:
Bioconversions. Hemisynthesis
Biological and medical sciences
Biotechnology
Esterification
Fundamental and applied biological sciences. Psychology
Hydrocinnamate
Lipase
Methods. Procedures. Technologies
Pseudomonas cepacia
Transesterification
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Summary:Lipase from Pseudomonas cepacia was used to prepare esters of hydrocinnamic acid by direct esterification of the carboxylic acid in good yields (70–83%). For some esters, transesterification gave better yields (92%). Optimization of the reaction conditions resulted in a dramatic increase in the yield of the product ester. The role of solvents was studied. Notably, cinnamic acid esters are not formed under these conditions.
ISSN:0141-0229
1879-0909
DOI:10.1016/S0141-0229(02)00340-X