Recombinant human platelet-derived growth factor-BB versus autologous bone graft in foot and ankle fusion: A systematic review and meta-analysis

Highlights • We analyzed outcomes of radiologic effectiveness, clinical results, and safety results between the two groups. • Results of analysis showed that rhPDGF-BB was as effective and safe as ABG in ankle and fusion fusion.

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Bibliographic Details
Published in:Foot and ankle surgery 2017-03, Vol.23 (1), p.32-39
Main Authors: Sun, Han, Lu, Pei-Pei, Zhou, Ping-Hui, Sun, Si-Wei, Zhang, Hong-Tao, Liu, Yi-Jie, Yang, Xu, Shen, Xiao-Feng, Yang, Hui-Lin
Format: Article
Language:English
Subjects:
Angiogenesis Inducing Agents - therapeutic use
Ankle fusion
Ankle Joint
Arthrodesis
Autogenous bone graft
Bone Transplantation
Humans
Joint Diseases - diagnosis
Joint Diseases - etiology
Joint Diseases - surgery
Meta-analysis
Orthopedics
Platelet derived growth factor
Proto-Oncogene Proteins c-sis - therapeutic use
Transplantation, Autologous
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Description
Summary:Highlights • We analyzed outcomes of radiologic effectiveness, clinical results, and safety results between the two groups. • Results of analysis showed that rhPDGF-BB was as effective and safe as ABG in ankle and fusion fusion.
ISSN:1268-7731
1460-9584
DOI:10.1016/j.fas.2016.02.001