Bioactivity, cytocompatibility and thermal properties of experimental Bioglass-reinforced composites as potential root-canal filling materials

To evaluate the bioactivity and the cytocompatibility of experimental Bioglass-reinforced polyethylene-based root-canal filling materials. The thermal properties of the experimental materials were also evaluated using differential scanning calorimetry, while their radiopacity was assessed using a gr...

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Bibliographic Details
Published in:Journal of the mechanical behavior of biomedical materials 2017-05, Vol.69, p.355-361
Main Authors: Alhashimi, Raghad Abdulrazzaq, Mannocci, Francesco, Sauro, Salvatore
Format: Article
Language:English
Subjects:
Bioactivity
Biocompatible Materials
Bioglass
Body Fluids
Cells, Cultured
Ceramics
Cytotoxicity
Humans
Materials Testing
Osteoblasts - cytology
Polyethylene
Root Canal Filling Materials
Root filling
Thermal properties
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Summary:To evaluate the bioactivity and the cytocompatibility of experimental Bioglass-reinforced polyethylene-based root-canal filling materials. The thermal properties of the experimental materials were also evaluated using differential scanning calorimetry, while their radiopacity was assessed using a grey-scale value (GSV) aluminium step wedge and a phosphor plate digital system. Bioglass 45S5 (BAG), polyethylene and Strontium oxide (SrO) were used to create tailored composite fibres. The filler distribution within the composites was assessed using SEM, while their bioactivity was evaluated through infrared spectroscopy (FTIR) after storage in simulated body fluid (SBF). The radiopacity of the composite fibres and their thermal properties were determined using differential scanning calorimetry (DSC). The cytocompatibility of the experimental composites used in this study was assessed using human osteoblasts and statistically analysed using the Pairwise t-test (p
ISSN:1751-6161
1878-0180
DOI:10.1016/j.jmbbm.2017.01.022