Serratia marcescens harboring SME-4 in Brazil: a silent threat

Abstract The intrinsic polymyxin resistance displayed by Serratia marcescens makes the acquisition of carbapenemase encoding genes a worrisome event. This study report a SME-4-producing S. marcescens isolate causing septic shock in Brazil. The insertion of novel resistance determinants and their con...

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Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 2017-04, Vol.87 (4), p.357-358
Main Authors: Cayô, Rodrigo, Leme, Rodrigo Cuiabano Paes, Streling, Ana Paula, Matos, Adriana Pereira, Nodari, Carolina Silva, Chaves, Jessica Reis Esteves, Brandão, Jorge Luiz Ferreira, de Almeida, Maíra Fernandes, Carrareto, Valério, de Castro Pereira, Marco Aurélio, de Almeida, Jean Pierre Aquino, Ferreira, Demian Candido, Gales, Ana Cristina
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - therapeutic use
Bacterial Proteins - metabolism
beta-Lactamases - metabolism
Brazil
Carbapenem resistance
Catheter-related bloodstream infection
Class A carbapenemase
Drug Resistance, Bacterial - drug effects
Enterobacteriaceae
Female
Humans
Infectious Disease
Internal Medicine
Microbial Sensitivity Tests
Middle Aged
Septic shock
Serine carbapenemase
Serratia
Serratia Infections - drug therapy
Serratia Infections - microbiology
Serratia marcescens - isolation & purification
Serratia marcescens - metabolism
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Summary:Abstract The intrinsic polymyxin resistance displayed by Serratia marcescens makes the acquisition of carbapenemase encoding genes a worrisome event. This study report a SME-4-producing S. marcescens isolate causing septic shock in Brazil. The insertion of novel resistance determinants and their consequent spread in our territory is noteworthy.
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2017.01.008