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Serratia marcescens harboring SME-4 in Brazil: a silent threat

Abstract The intrinsic polymyxin resistance displayed by Serratia marcescens makes the acquisition of carbapenemase encoding genes a worrisome event. This study report a SME-4-producing S. marcescens isolate causing septic shock in Brazil. The insertion of novel resistance determinants and their con...

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Published in:Diagnostic microbiology and infectious disease 2017-04, Vol.87 (4), p.357-358
Main Authors: Cayô, Rodrigo, Leme, Rodrigo Cuiabano Paes, Streling, Ana Paula, Matos, Adriana Pereira, Nodari, Carolina Silva, Chaves, Jessica Reis Esteves, Brandão, Jorge Luiz Ferreira, de Almeida, Maíra Fernandes, Carrareto, Valério, de Castro Pereira, Marco Aurélio, de Almeida, Jean Pierre Aquino, Ferreira, Demian Candido, Gales, Ana Cristina
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cited_by cdi_FETCH-LOGICAL-c505t-254c9954db6d4e56d9721ecf015b28521bcdbe4014d64a1681a5a28e5ab1d2e93
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container_end_page 358
container_issue 4
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container_title Diagnostic microbiology and infectious disease
container_volume 87
creator Cayô, Rodrigo
Leme, Rodrigo Cuiabano Paes
Streling, Ana Paula
Matos, Adriana Pereira
Nodari, Carolina Silva
Chaves, Jessica Reis Esteves
Brandão, Jorge Luiz Ferreira
de Almeida, Maíra Fernandes
Carrareto, Valério
de Castro Pereira, Marco Aurélio
de Almeida, Jean Pierre Aquino
Ferreira, Demian Candido
Gales, Ana Cristina
description Abstract The intrinsic polymyxin resistance displayed by Serratia marcescens makes the acquisition of carbapenemase encoding genes a worrisome event. This study report a SME-4-producing S. marcescens isolate causing septic shock in Brazil. The insertion of novel resistance determinants and their consequent spread in our territory is noteworthy.
doi_str_mv 10.1016/j.diagmicrobio.2017.01.008
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source ScienceDirect Journals
subjects Anti-Bacterial Agents - therapeutic use
Bacterial Proteins - metabolism
beta-Lactamases - metabolism
Brazil
Carbapenem resistance
Catheter-related bloodstream infection
Class A carbapenemase
Drug Resistance, Bacterial - drug effects
Enterobacteriaceae
Female
Humans
Infectious Disease
Internal Medicine
Microbial Sensitivity Tests
Middle Aged
Septic shock
Serine carbapenemase
Serratia
Serratia Infections - drug therapy
Serratia Infections - microbiology
Serratia marcescens - isolation & purification
Serratia marcescens - metabolism
title Serratia marcescens harboring SME-4 in Brazil: a silent threat
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