Profile of Tuberculous Cervical Lymphadenopathy in Children

• Published in: Journal of tropical pediatrics (1980) 2017-10, Vol.63 (5), p.395-398
• Main Authors: Shah, Ira, Dani, Samruddhi
• Format: Article
• Language: English
• Subjects: Adolescent; Antitubercular Agents - therapeutic use; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; India - epidemiology; Infant; Male; Mycobacterium tuberculosis - isolation & purification; Prevalence; Treatment Outcome; Tuberculosis, Lymph Node - diagnosis; Tuberculosis, Lymph Node - drug therapy; Tuberculosis, Lymph Node - epidemiology; Tuberculosis, Multidrug-Resistant - drug therapy; Ultrasonography
• ISSN: 0142-6338; 1465-3664
• DOI: 10.1093/tropej/fmx001

Analyze clinical profile of tuberculous cervical lymphadenopathy in children. Of 1582 children with tuberculosis (TB), 63 (4%) had tuberculous cervical lymphadenopathy. The mean age at presentation was 7.4 ± 3.8 years (range of 1-14 years). Twenty-nine (46%) patients had bilateral lymphadenopathy, 17 (27%) each had left-sided and right-sided nodes. In 22 cases, culture was done, and 13 (59.1%) grew Mycobacterium tuberculosis of which 6 (46.2%) were drug resistant-1 (16.7%) was polyresistant, 1 (16.7%) was extremely drug resistant (XDR) and 4 (66.7%) were pre-XDR TB. Fifteen (23.8%) patients had TB in the past, of which 7 (46.7%) had previous cervical lymphadenopathy, 6 (40%) had pulmonary TB, 1 (6.7%) multifocal lymphadenopathy and 1 (6.7%) disseminated TB. Contact with a TB patient had occurred in 25 (39.7%) cases. Tuberculous cervical lymphadenopathy is not so common in children. Bilateral involvement was more common. Mean age at presentation was 7.4 years. Drug resistance was prevalent in these patients.