Effects of glucocorticoid-induced osteoporosis on bone tissue of rats with experimental periodontitis

Highlights • GIOP worsens ABL in animals subjected to EP. • GIOP causes a greater decrease in osteoblast activity in animals subjected to EP. • GIOP causes bone loss in femur of animals subjected to EP.

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Bibliographic Details
Published in:Archives of oral biology 2017-05, Vol.77, p.55-61
Main Authors: Sousa, Luzia Hermínia Teixeira, Moura, Eveline Valeriano, Queiroz, Ana Larissa, Val, Danielle, Chaves, Hellíada, Lisboa, Mario, Furlaneto, Flávia, Brito, Gerly Anne, Goes, Paula
Format: Article
Language:English
Subjects:
Advanced Basic Science
Alkaline Phosphatase - blood
Alveolar bone loss
Animals
Bone Density - drug effects
Dentistry
Femur - diagnostic imaging
Femur - drug effects
Glucocorticoids
Glucocorticoids - toxicity
Male
Osteoporosis
Osteoporosis - chemically induced
Osteoporosis - diagnostic imaging
Osteoporosis - pathology
Periodontitis
Periodontitis - complications
Rats
Rats, Wistar
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Description
Summary:Highlights • GIOP worsens ABL in animals subjected to EP. • GIOP causes a greater decrease in osteoblast activity in animals subjected to EP. • GIOP causes bone loss in femur of animals subjected to EP.
ISSN:0003-9969
1879-1506
DOI:10.1016/j.archoralbio.2017.01.014