Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)

Osteosarcoma (OS) is the most common type of bone cancer, especially in young. Telangiectatic osteosarcoma (TO) is a rare variant of OS, and hence, its occurrence, presentation, and prognosis are poorly understood. A 4-year-old female rhesus monkey presenting lameness and swelling was examined for a...

Full description

Saved in:
Bibliographic Details
Published in:Journal of medical primatology 2017, Vol.46 (2), p.51-55
Main Authors: Goldschmidt, B, Calado, M I Z, Resende, F C, Caldas, R M, Pinto, L W, Lopes, C A A, França, F G O, Meireles, B S, Souza, I V
Format: Report
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 55
container_issue 2
container_start_page 51
container_title Journal of medical primatology
container_volume 46
creator Goldschmidt, B
Calado, M I Z
Resende, F C
Caldas, R M
Pinto, L W
Lopes, C A A
França, F G O
Meireles, B S
Souza, I V
description Osteosarcoma (OS) is the most common type of bone cancer, especially in young. Telangiectatic osteosarcoma (TO) is a rare variant of OS, and hence, its occurrence, presentation, and prognosis are poorly understood. A 4-year-old female rhesus monkey presenting lameness and swelling was examined for a mass on the right humerus. Radiography revealed fracture and disorganized structure of bone tissue. Histopathological examination revealed malignant neoplasm composed of anaplastic osteoblasts, which invaded the bone marrow and surrounded blood-filled cysts in the epiphysis and diaphysis forming septa. Cytogenetic analysis showed aneuploid cells, supernumerary AgNORs, and a marker fragment. The neoplasm was diagnosed as TO. To our knowledge, the occurrence of TO and its cytogenetic analysis were reported for the first time in non-human primates.
doi_str_mv 10.1111/jmp.12254
format report
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_1867540969</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1867540969</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_18675409693</originalsourceid><addsrcrecordid>eNqVzbsKwjAYBeAgCNbL4BtkrIM1adPYzqI46KR7-QlRU3Kp_dP3t6Av4FnOGT44hKw5y_iYXeu6jOd5KSYk4ZKxLZOVmJE5YssYK0QtEnK5dcFH8DoMSKO24J9GqwjRKBow6oDQq-CAGk-B9i-No3Og4D1oml7HoYC6wUKMsFmS6QMs6tWvFyQ9He-H87brw-gxNs6g0tZ-_xpeyX0pWC3r4g_6ASQLRVw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>report</recordtype><pqid>1867540969</pqid></control><display><type>report</type><title>Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)</title><source>Wiley-Blackwell Read &amp; Publish Collection</source><creator>Goldschmidt, B ; Calado, M I Z ; Resende, F C ; Caldas, R M ; Pinto, L W ; Lopes, C A A ; França, F G O ; Meireles, B S ; Souza, I V</creator><creatorcontrib>Goldschmidt, B ; Calado, M I Z ; Resende, F C ; Caldas, R M ; Pinto, L W ; Lopes, C A A ; França, F G O ; Meireles, B S ; Souza, I V</creatorcontrib><description>Osteosarcoma (OS) is the most common type of bone cancer, especially in young. Telangiectatic osteosarcoma (TO) is a rare variant of OS, and hence, its occurrence, presentation, and prognosis are poorly understood. A 4-year-old female rhesus monkey presenting lameness and swelling was examined for a mass on the right humerus. Radiography revealed fracture and disorganized structure of bone tissue. Histopathological examination revealed malignant neoplasm composed of anaplastic osteoblasts, which invaded the bone marrow and surrounded blood-filled cysts in the epiphysis and diaphysis forming septa. Cytogenetic analysis showed aneuploid cells, supernumerary AgNORs, and a marker fragment. The neoplasm was diagnosed as TO. To our knowledge, the occurrence of TO and its cytogenetic analysis were reported for the first time in non-human primates.</description><identifier>EISSN: 1600-0684</identifier><identifier>DOI: 10.1111/jmp.12254</identifier><language>eng</language><ispartof>Journal of medical primatology, 2017, Vol.46 (2), p.51-55</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>776,780,4476,27902</link.rule.ids></links><search><creatorcontrib>Goldschmidt, B</creatorcontrib><creatorcontrib>Calado, M I Z</creatorcontrib><creatorcontrib>Resende, F C</creatorcontrib><creatorcontrib>Caldas, R M</creatorcontrib><creatorcontrib>Pinto, L W</creatorcontrib><creatorcontrib>Lopes, C A A</creatorcontrib><creatorcontrib>França, F G O</creatorcontrib><creatorcontrib>Meireles, B S</creatorcontrib><creatorcontrib>Souza, I V</creatorcontrib><title>Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)</title><title>Journal of medical primatology</title><description>Osteosarcoma (OS) is the most common type of bone cancer, especially in young. Telangiectatic osteosarcoma (TO) is a rare variant of OS, and hence, its occurrence, presentation, and prognosis are poorly understood. A 4-year-old female rhesus monkey presenting lameness and swelling was examined for a mass on the right humerus. Radiography revealed fracture and disorganized structure of bone tissue. Histopathological examination revealed malignant neoplasm composed of anaplastic osteoblasts, which invaded the bone marrow and surrounded blood-filled cysts in the epiphysis and diaphysis forming septa. Cytogenetic analysis showed aneuploid cells, supernumerary AgNORs, and a marker fragment. The neoplasm was diagnosed as TO. To our knowledge, the occurrence of TO and its cytogenetic analysis were reported for the first time in non-human primates.</description><issn>1600-0684</issn><fulltext>true</fulltext><rsrctype>report</rsrctype><creationdate>2017</creationdate><recordtype>report</recordtype><recordid>eNqVzbsKwjAYBeAgCNbL4BtkrIM1adPYzqI46KR7-QlRU3Kp_dP3t6Av4FnOGT44hKw5y_iYXeu6jOd5KSYk4ZKxLZOVmJE5YssYK0QtEnK5dcFH8DoMSKO24J9GqwjRKBow6oDQq-CAGk-B9i-No3Og4D1oml7HoYC6wUKMsFmS6QMs6tWvFyQ9He-H87brw-gxNs6g0tZ-_xpeyX0pWC3r4g_6ASQLRVw</recordid><startdate>20170401</startdate><enddate>20170401</enddate><creator>Goldschmidt, B</creator><creator>Calado, M I Z</creator><creator>Resende, F C</creator><creator>Caldas, R M</creator><creator>Pinto, L W</creator><creator>Lopes, C A A</creator><creator>França, F G O</creator><creator>Meireles, B S</creator><creator>Souza, I V</creator><scope>7X8</scope></search><sort><creationdate>20170401</creationdate><title>Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)</title><author>Goldschmidt, B ; Calado, M I Z ; Resende, F C ; Caldas, R M ; Pinto, L W ; Lopes, C A A ; França, F G O ; Meireles, B S ; Souza, I V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_18675409693</frbrgroupid><rsrctype>reports</rsrctype><prefilter>reports</prefilter><language>eng</language><creationdate>2017</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Goldschmidt, B</creatorcontrib><creatorcontrib>Calado, M I Z</creatorcontrib><creatorcontrib>Resende, F C</creatorcontrib><creatorcontrib>Caldas, R M</creatorcontrib><creatorcontrib>Pinto, L W</creatorcontrib><creatorcontrib>Lopes, C A A</creatorcontrib><creatorcontrib>França, F G O</creatorcontrib><creatorcontrib>Meireles, B S</creatorcontrib><creatorcontrib>Souza, I V</creatorcontrib><collection>MEDLINE - Academic</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goldschmidt, B</au><au>Calado, M I Z</au><au>Resende, F C</au><au>Caldas, R M</au><au>Pinto, L W</au><au>Lopes, C A A</au><au>França, F G O</au><au>Meireles, B S</au><au>Souza, I V</au><format>book</format><genre>unknown</genre><ristype>RPRT</ristype><atitle>Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)</atitle><jtitle>Journal of medical primatology</jtitle><date>2017-04-01</date><risdate>2017</risdate><volume>46</volume><issue>2</issue><spage>51</spage><epage>55</epage><pages>51-55</pages><eissn>1600-0684</eissn><abstract>Osteosarcoma (OS) is the most common type of bone cancer, especially in young. Telangiectatic osteosarcoma (TO) is a rare variant of OS, and hence, its occurrence, presentation, and prognosis are poorly understood. A 4-year-old female rhesus monkey presenting lameness and swelling was examined for a mass on the right humerus. Radiography revealed fracture and disorganized structure of bone tissue. Histopathological examination revealed malignant neoplasm composed of anaplastic osteoblasts, which invaded the bone marrow and surrounded blood-filled cysts in the epiphysis and diaphysis forming septa. Cytogenetic analysis showed aneuploid cells, supernumerary AgNORs, and a marker fragment. The neoplasm was diagnosed as TO. To our knowledge, the occurrence of TO and its cytogenetic analysis were reported for the first time in non-human primates.</abstract><doi>10.1111/jmp.12254</doi></addata></record>
fulltext fulltext
identifier EISSN: 1600-0684
ispartof Journal of medical primatology, 2017, Vol.46 (2), p.51-55
issn 1600-0684
language eng
recordid cdi_proquest_miscellaneous_1867540969
source Wiley-Blackwell Read & Publish Collection
title Spontaneous telangiectatic osteosarcoma in a rhesus macaque (Macaca mulatta)
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-22T08%3A16%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=unknown&rft.atitle=Spontaneous%20telangiectatic%20osteosarcoma%20in%20a%20rhesus%20macaque%20(Macaca%20mulatta)&rft.jtitle=Journal%20of%20medical%20primatology&rft.au=Goldschmidt,%20B&rft.date=2017-04-01&rft.volume=46&rft.issue=2&rft.spage=51&rft.epage=55&rft.pages=51-55&rft.eissn=1600-0684&rft_id=info:doi/10.1111/jmp.12254&rft_dat=%3Cproquest%3E1867540969%3C/proquest%3E%3Cgrp_id%3Ecdi_FETCH-proquest_miscellaneous_18675409693%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1867540969&rft_id=info:pmid/&rfr_iscdi=true