Impact of body mass index on the oncological outcomes of patients treated with radical cystectomy for muscle-invasive bladder cancer

Purpose Body mass index (BMI) has been associated with worse outcomes in several solid malignancies. We aimed to evaluate the association between BMI and oncological outcomes in patients treated with radical cystectomy (RC) for muscle-invasive urothelial carcinoma of the bladder (UCB). Methods We re...

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Bibliographic Details
Published in:World journal of urology 2017-02, Vol.35 (2), p.229-235
Main Authors: Dabi, Yohann, Rouscoff, Yohann, Anract, Julien, Delongchamps, Nicolas Barry, Sibony, Mathilde, Saighi, Djillali, Zerbib, Marc, Peyraumore, Michael, Xylinas, Evanguelos
Format: Article
Language:English
Subjects:
Aged
Bladder cancer
Body Mass Index
Carcinoma, Transitional Cell - mortality
Carcinoma, Transitional Cell - pathology
Carcinoma, Transitional Cell - surgery
Cystectomy
Female
Humans
Male
Medicine
Medicine & Public Health
Muscle, Smooth
Neoplasm Invasiveness
Neoplasm Recurrence, Local - epidemiology
Nephrology
Oncology
Original Article
Retrospective Studies
Survival Rate
Treatment Outcome
Urinary Bladder Neoplasms - mortality
Urinary Bladder Neoplasms - pathology
Urinary Bladder Neoplasms - surgery
Urology
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Summary:Purpose Body mass index (BMI) has been associated with worse outcomes in several solid malignancies. We aimed to evaluate the association between BMI and oncological outcomes in patients treated with radical cystectomy (RC) for muscle-invasive urothelial carcinoma of the bladder (UCB). Methods We retrospectively reviewed 701 consecutive patients treated with RC and pelvic lymphadenectomy for UCB at our institution between 1995 and 2011. Univariable and multivariable Cox regression models investigated the association of BMI with disease recurrence and cancer-specific mortality. BMI was analyzed as both continuous and categorical variable (
ISSN:0724-4983
1433-8726
DOI:10.1007/s00345-016-1852-0