Multi‐institutional experience of stereotactic body radiotherapy for large (≥5 centimeters) non–small cell lung tumors

• Published in: Cancer 2017-02, Vol.123 (4), p.688-696
• Main Authors: Verma, Vivek, Shostrom, Valerie K., Kumar, Sameera S., Zhen, Weining, Hallemeier, Christopher L., Braunstein, Steve E., Holland, John, Harkenrider, Matthew M., S. Iskhanian, Adrian, Neboori, Hanmanth J., Jabbour, Salma K., Attia, Albert, Lee, Percy, Alite, Fiori, Walker, Joshua M., Stahl, John M., Wang, Kyle, Bingham, Brian S., Hadzitheodorou, Christina, Decker, Roy H., McGarry, Ronald C., Simone, Charles B.
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Cancer; Carcinoma, Non-Small-Cell Lung - epidemiology; Carcinoma, Non-Small-Cell Lung - pathology; Carcinoma, Non-Small-Cell Lung - radiotherapy; chemotherapy; Dermatitis; Disease-Free Survival; Dose Fractionation, Radiation; Emission analysis; Female; Follow-Up Studies; Fractionation; Hazards; Humans; image‐guided radiotherapy; Institutions; Kaplan-Meier Estimate; Lung cancer; Lymph; Lymph nodes; Lymphatic Metastasis; Male; Metastases; Middle Aged; Multivariate analysis; Neoplasm Recurrence, Local - epidemiology; Neoplasm Recurrence, Local - pathology; Neoplasm Recurrence, Local - radiotherapy; Non-small cell lung carcinoma; non–small cell lung cancer; Oncology; Patients; Pneumonitis; Positron emission; Positron emission tomography; Quality; Radiation; Radiation dosage; Radiation therapy; Radiosurgery; Smoking; Statistical analysis; stereotactic body radiotherapy; Survival; Terminology; Toxicity; Treatment Outcome; Tumors
• ISSN: 0008-543X; 1097-0142
• DOI: 10.1002/cncr.30375

BACKGROUND Stereotactic body radiotherapy (SBRT) is the standard of care for patients with nonoperative, early‐stage non–small cell lung cancer (NSCLC) measuring