Performance evaluation of a rapid molecular diagnostic, MultiCode based, sample-to-answer assay for the simultaneous detection of Influenza A, B and Respiratory Syncytial Viruses

Highlights • ARIES FluA/B and RSV assay is an easy-to-use molecular point of impact assay. • Clinical sensitivity and specificity is comparable to laboratory developed assays. • Clinical sensitivity is significantly better than that of DFA and ICT rapid tests. • Pre-treatment of viscous samples is r...

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Bibliographic Details
Published in:Journal of clinical virology 2016-12, Vol.85, p.65-70
Main Authors: Voermans, Jolanda J.C, Seven-Deniz, S, Fraaij, P.L.A, van der Eijk, Annemiek A, Koopmans, M.P.G, Pas, Suzan D
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Allergy and Immunology
Aries luminex
Child
Child, Preschool
DFA
Direct immunofluorescence assay
Female
Humans
ICT
Immunochromatography test
Infant
Infant, Newborn
Infectious Disease
Influenza A virus - genetics
Influenza A virus - isolation & purification
Influenza B virus - genetics
Influenza B virus - isolation & purification
Male
Middle Aged
Molecular Diagnostic Techniques - methods
MultiCode
Point of impact
Rapid test
Real-time PCR
Respiratory Syncytial Viruses - genetics
Respiratory Syncytial Viruses - isolation & purification
Respiratory Tract Infections - diagnosis
Sensitivity and Specificity
Time Factors
Virus Diseases - diagnosis
Young Adult
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Description
Summary:Highlights • ARIES FluA/B and RSV assay is an easy-to-use molecular point of impact assay. • Clinical sensitivity and specificity is comparable to laboratory developed assays. • Clinical sensitivity is significantly better than that of DFA and ICT rapid tests. • Pre-treatment of viscous samples is recommended for ARIES.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2016.10.019