Status of Iron Metabolism 10 Years After Roux-En-Y Gastric Bypass

Background The aim of this study is to investigate changes in iron metabolism and verify whether biochemical parameters are related to the use of oral iron supplement 10 years after Roux-en-Y gastric bypass. Methods This longitudinal retrospective study included 151 patients submitted to Roux-en-Y g...

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Bibliographic Details
Published in:Obesity surgery 2017-08, Vol.27 (8), p.1993-1999
Main Authors: Monaco-Ferreira, Daniela Vicinansa, Leandro-Merhi, Vânia Aparecida
Format: Article
Language:English
Subjects:
Administration, Oral
Adult
Anemia, Iron-Deficiency - blood
Anemia, Iron-Deficiency - metabolism
Dietary Supplements
Female
Gastric Bypass
Gastrointestinal surgery
Humans
Iron
Iron - blood
Iron - metabolism
Longitudinal Studies
Male
Medicine
Medicine & Public Health
Metabolism
Middle Aged
Obesity
Obesity, Morbid - metabolism
Obesity, Morbid - surgery
Original Contributions
Retrospective Studies
Surgery
Surgical outcomes
Time Factors
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Summary:Background The aim of this study is to investigate changes in iron metabolism and verify whether biochemical parameters are related to the use of oral iron supplement 10 years after Roux-en-Y gastric bypass. Methods This longitudinal retrospective study included 151 patients submitted to Roux-en-Y gastric bypass. The collected data included use of an oral iron supplement, hemoglobin, hematocrit, serum iron, and ferritin. The chi-squared or Fisher’s exact test was used to analyze the association between use of iron supplement and nutritional deficiency. The generalized estimating equations (GEEs) analyzed the nutritional deficiencies over time. Results Of the study patients with iron-deficiency anemia ( n  = 15) in the 12-month follow-up, 73.33% ( n  = 11) were taking an iron supplement, and 26.67% ( n  = 4) were not ( p  = 0.0010). The effect of time was significant for hemoglobin, ferritin, iron overload ( p  
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-017-2582-0