Intravenous immunoglobulin modulates lymphocyte CD54 and monocyte FcγRII expression in patients with chronic inflammatory neuropathies

We studied the expression of different lymphocyte and monocyte cellular determinants involved in leukodiapedesis and antigen presentation in 10 patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and multifocal motor neuropathy (MMN) with persistent conduction blocks befor...

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Bibliographic Details
Published in:Journal of neuroimmunology 2003-02, Vol.135 (1), p.91-95
Main Authors: Créange, A, Gregson, N.A, Hughes, R.A.C
Format: Article
Language:English
Subjects:
Inflammatory neuropathy
Integrins
Intravenous immunoglobulin
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Summary:We studied the expression of different lymphocyte and monocyte cellular determinants involved in leukodiapedesis and antigen presentation in 10 patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and multifocal motor neuropathy (MMN) with persistent conduction blocks before intravenous immunoglobulin (IVIg), immediately after infusion of IVIg and 1 week after infusion. We observed a decrease of T lymphocytes expressing ICAM-1 (CD54) immediately after infusion in 8 out of 10 patients ( p
ISSN:0165-5728
1872-8421
DOI:10.1016/S0165-5728(02)00430-7