Reply to Letter to the Editor on “Intravenous Versus Intra-articular Tranexamic Acid in Total Knee Arthroplasty: A Double-blinded Randomised Controlled Noninferiority Trial”

The choice for a fixed time interval to record postoperative Hb level and total blood loss reduces variability in our study methodology, compared to using the lowest Hb value during the inpatient stay recorded on a random day. Furthermore, there are also other studies comparing intravenous (IV) vers...

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Bibliographic Details
Published in:The knee 2017-06, Vol.24 (3), p.700-701
Main Authors: Chen, Jerry Yongqiang, Chin, Pak Lin, Moo, Ing How, Pang, Hee Nee, Tay, Darren Keng Jin, Chia, Shi-Lu, Lo, Ngai Nung, Yeo, Seng Jin
Format: Article
Language:English
Subjects:
Acids
Antifibrinolytic agents
Arthroplasty (knee)
Blood
Hemorrhage
Intravenous administration
Joint surgery
Knee
Orthopedics
Sharks
Studies
Citations: Items that this one cites
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Summary:The choice for a fixed time interval to record postoperative Hb level and total blood loss reduces variability in our study methodology, compared to using the lowest Hb value during the inpatient stay recorded on a random day. Furthermore, there are also other studies comparing intravenous (IV) versus intra-articular (IA) tranexamic acid (TXA) that reported postoperative Hb level and total blood loss on POD 1 [2,3]. The Mann-Whitney U test was used to compare IV versus IA TXA for continuous variables with non-normal distribution, hence the median and interquartile range (IQR) were reported rather than the mean and standard deviation.
ISSN:0968-0160
1873-5800
DOI:10.1016/j.knee.2016.07.006