Frozen Sections in Patients Undergoing Breast Conserving Surgery at a Single Ambulatory Surgical Center: 5 Year Experience

• Published in: European journal of surgical oncology 2017-07, Vol.43 (7), p.1273-1281
• Main Authors: Jorns, Julie M., M.D, Daignault, Stephanie, M.S, Sabel, Michael S., M.D, Myers, Jeffrey L., M.D, Wu, Angela J., M.D
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Breast cancer; Breast conserving therapy; Breast Neoplasms - pathology; Breast Neoplasms - surgery; Breast Neoplasms, Male - pathology; Breast Neoplasms, Male - surgery; Carcinoma, Ductal, Breast - pathology; Carcinoma, Ductal, Breast - surgery; Carcinoma, Intraductal, Noninfiltrating - pathology; Carcinoma, Intraductal, Noninfiltrating - surgery; Carcinoma, Lobular - pathology; Carcinoma, Lobular - surgery; Female; Frozen section; Frozen Sections - trends; Frozen Sections - utilization; Hematology, Oncology and Palliative Medicine; Humans; Intraoperative; Intraoperative Period; Male; Margins of Excision; Mastectomy, Segmental - methods; Middle Aged; Reoperation; Sentinel Lymph Node - pathology; Sentinel Lymph Node Biopsy - methods; Surgery; Surgicenters; Tumor Burden; Young Adult
• ISSN: 0748-7983; 1532-2157
• DOI: 10.1016/j.ejso.2017.01.237

Abstract Objectives To evaluate outcomes of our breast frozen section (FS) practice in its first 5 years, including our specialized FS of margins (FSM) procedure for breast conserving therapy (BCT) patients. Methods 1248 patients undergoing 1303 breast FSM and/or sentinel lymph node (SLN) FS were included. Clinicopathologic features were assessed by chart review. Results Use of SLN FS declined, from 43.5% of FS cases before to 19.2% of FS cases after 2012. FSM patients had a decline in overall reexcision to 12.3% in 2013-2014 (p=0.063). There was also decline in reexcision for focally close margins (p