Hyperbaric oxygen therapy for chronic ulcers in systemic sclerosis – case series

Background Digital and leg ulcers are extremely painful, hard to heal manifestations of systemic sclerosis (SSc). Many treatments have been tried for these challenging complications, but use of hyperbaric oxygen therapy (HBOT) is very limited. HBOT has been used as an adjunctive therapy for treating...

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Bibliographic Details
Published in:International journal of dermatology 2017-06, Vol.56 (6), p.636-640
Main Authors: Mirasoglu, Bengusu, Bagli, Bekir S., Aktas, Samil
Format: Article
Language:English
Subjects:
Adult
Amputation
Complications
Demographics
Demography
Female
Fingers
Healing
Humans
Hyperbaric oxygen therapy
Hyperbaric Oxygenation
Hypoxia
Leg
Leg Ulcer - etiology
Leg Ulcer - therapy
Leg ulcers
Lesions
Male
Middle Aged
Oxygen therapy
Patients
Retrospective Studies
Scleroderma
Scleroderma, Systemic - complications
Systemic sclerosis
Therapy
Toes
Treatment Outcome
Ulcers
Wound Healing
Wounds
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Summary:Background Digital and leg ulcers are extremely painful, hard to heal manifestations of systemic sclerosis (SSc). Many treatments have been tried for these challenging complications, but use of hyperbaric oxygen therapy (HBOT) is very limited. HBOT has been used as an adjunctive therapy for treating chronic wounds, and nonhealing SSc wounds, which have a hypoxic nature, may also benefit from it. Methods This is a retrospective analysis of six SSc patients who underwent HBOT for their ulcers. Patient demographics, ulcer properties, and details of treatments were evaluated. Results Three patients had digital ulcers, and the other three had leg ulcers. Three patients (two leg ulcers and one digital ulcer) had bilateral lesions. All patients had been treated for at least one and a half months with various modalities. After HBOT was applied, four patients’ ulcers healed completely and two patients had near‐complete healing. Amputation was not required for any. Conclusion This case series, which has the largest patient population up to present, shows adjunctive HBOT may be helpful in the treatment of SSc ulcers.
ISSN:0011-9059
1365-4632
DOI:10.1111/ijd.13570