Sarcopenia and sarcopenic obesity in comparison: prevalence, metabolic profile, and key differences. A cross-sectional study in Italian hospitalized elderly

Background The aim of this study is to identify the prevalence, assess the metabolic profile, and key differences (versus healthy) in a cohort of subjects with sarcopenia (S) and in sarcopenic obesity (SO) hospitalized elderly. Methods A standardized comprehensive geriatric assessment was performed....

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Published in:Aging clinical and experimental research 2017-12, Vol.29 (6), p.1249-1258
Main Authors: Perna, Simone, Peroni, Gabriella, Faliva, Milena Anna, Bartolo, Arianna, Naso, Maurizio, Miccono, Alessandra, Rondanelli, Mariangela
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Analysis of Variance
Biomarkers - blood
Case-Control Studies
Cross-Sectional Studies
Edema
Female
Fractures
Geriatric Assessment
Geriatrics/Gerontology
Humans
Inflammation
Male
Malnutrition
Medicine
Medicine & Public Health
Metabolism
Metabolome
Nutritional Status - physiology
Obesity
Obesity - epidemiology
Obesity - physiopathology
Original Article
Osteoporosis
Prevalence
Risk Factors
Sarcopenia
Sarcopenia - blood
Sarcopenia - epidemiology
Sarcopenia - physiopathology
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Summary:Background The aim of this study is to identify the prevalence, assess the metabolic profile, and key differences (versus healthy) in a cohort of subjects with sarcopenia (S) and in sarcopenic obesity (SO) hospitalized elderly. Methods A standardized comprehensive geriatric assessment was performed. We enrolled 639 elderly subjects (196 men, 443 women) with a mean age of 80.90 ± 7.77 years. Analysis of variance and a multinomial logistic regression analysis adjusting for covariates were used to assess the differences between groups. Results The prevalence of (S) was 12.42% in women and 23.47% in men. (SO) was 8.13% in women and 22.45% in men. Data showed that either groups had a functional impairment (Barthel index 15 mm/h), CPR (>0.50 mg/dl) homocysteine (>12 micromol/l), and hemoglobin (145 mcg/dl) was detected in either cohort (due to inflammation). (SO) had glycemia (>110 mg/dl). Key differences in (S) cohort (versus healthy) were a reduction in functional impairment ( p  
ISSN:1720-8319
1594-0667
1720-8319
DOI:10.1007/s40520-016-0701-8