Evidence for alterations of the right inferior and superior longitudinal fasciculi in patients with social anxiety disorder

Highlights • FA was reduced in the right ILF and SLF in SAD group than in controls. • FA was negatively correlated with SAD symptom severity. • RD was positively correlated with SAD symptom severity. • WM abnormality in the right SLF and ILF may be implicated in the pathophysiology of SAD.

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Bibliographic Details
Published in:Brain research 2017-05, Vol.1662, p.16-22
Main Authors: Tükel, Raşit, Ulasoglu Yildiz, Cigdem, Ertekin, Erhan, Kurt, Elif, Koyuncu, Ahmet, Aydın, Kubilay
Format: Article
Language:English
Subjects:
Adult
Anisotropy
Brain - physiopathology
Diffusion tensor imaging
Diffusion Tensor Imaging - methods
Female
Fractional anisotropy
Humans
Image Processing, Computer-Assisted
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
Nerve Fibers, Myelinated
Nerve Net - physiopathology
Neurology
Phobia, Social - metabolism
Phobia, Social - physiopathology
Social anxiety disorder
White matter
White Matter - physiopathology
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Summary:Highlights • FA was reduced in the right ILF and SLF in SAD group than in controls. • FA was negatively correlated with SAD symptom severity. • RD was positively correlated with SAD symptom severity. • WM abnormality in the right SLF and ILF may be implicated in the pathophysiology of SAD.
ISSN:0006-8993
1872-6240
DOI:10.1016/j.brainres.2017.02.016