Impact of a restrictive vs liberal transfusion strategy on anastomotic leakage and infectious complications after restorative surgery for rectal cancer

Aim The aim of this study was to investigate the impact of a restrictive vs liberal transfusion strategy on anastomotic leakage and infectious complications after rectal cancer surgery. Methods Patients undergoing restorative proctectomy for rectal cancer between January 2008 and December 2013 were...

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Bibliographic Details
Published in:Colorectal disease 2017-08, Vol.19 (8), p.772-780
Main Authors: Ozben, V., Stocchi, L., Ashburn, J., Liu, X., Gorgun, E.
Format: Article
Language:English
Subjects:
Aged
Albumin
Anastomotic Leak - etiology
Anastomotic Leak - therapy
anastomotic leakage
Blood transfusion
Blood Transfusion - methods
Cancer
Cancer surgery
Complications
Databases, Factual
Female
Hemoglobin
Hemoglobins - analysis
Humans
infectious complications
Leakage
Male
Margins of Excision
Middle Aged
Multivariate analysis
Preoperative Period
Proctocolectomy, Restorative - adverse effects
Prospective Studies
Radiation therapy
rectal cancer surgery
Rectal Neoplasms - blood
Rectal Neoplasms - pathology
Rectal Neoplasms - surgery
Rectum
Retrospective Studies
Risk Factors
Serum Albumin - analysis
Surgery
Surgical site infections
Surgical Wound Infection - etiology
Surgical Wound Infection - therapy
Transfusion
Transfusion Reaction - etiology
Transfusion threshold
Treatment Outcome
Tumor Burden
Tumors
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Summary:Aim The aim of this study was to investigate the impact of a restrictive vs liberal transfusion strategy on anastomotic leakage and infectious complications after rectal cancer surgery. Methods Patients undergoing restorative proctectomy for rectal cancer between January 2008 and December 2013 were divided into four groups according to the perioperative lowest haemoglobin (Hgb) level and transfusion status: group 1 with Hgb level ≥ 10 g/dl; group 2 with Hgb level ≥ 7 and
ISSN:1462-8910
1463-1318
DOI:10.1111/codi.13641