Number of embryos biopsied as a predictive indicator for the outcome of preimplantation genetic diagnosis by fluorescence in situ hybridisation in translocation cases

This study aimed to investigate the optimum number of embryos to be biopsied in order to increase the likelihood of obtaining a balanced/normal embryo following preimplantation genetic diagnosis (PGD) by fluorescence in situ hybridisation (FISH) for translocation carriers. Patients with low number o...

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Bibliographic Details
Published in:Zygote (Cambridge) 2016-02, Vol.24 (1), p.107-114
Main Authors: Tulay, P., Gultomruk, M., Findikli, N., Bahceci, M.
Format: Article
Language:English
Subjects:
Adult
Biopsy
Blastocyst
Blastomeres - physiology
Embryo Transfer
Embryos
Female
Fluorescence
Humans
In Situ Hybridization, Fluorescence - methods
Male
Maternal Age
Ovulation Induction
Pregnancy
Pregnancy Rate
Preimplantation Diagnosis - methods
Sperm Injections, Intracytoplasmic
Translocation
Translocation, Genetic
Vitrification
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Summary:This study aimed to investigate the optimum number of embryos to be biopsied in order to increase the likelihood of obtaining a balanced/normal embryo following preimplantation genetic diagnosis (PGD) by fluorescence in situ hybridisation (FISH) for translocation carriers. Patients with low number of fertilised oocytes (≤5) or low number of embryos available for PGD (
ISSN:0967-1994
1469-8730
DOI:10.1017/S0967199414000793