The Microbiome and Risk for Obesity and Diabetes

Obesity and type 2 diabetes mellitus are influenced both by genes and lifestyle. That is not news. However, the genes in the human microbiome also may play an important role, and that is news. It has been known for decades that gut bacteria synthesize essential vitamins and amino acids and help degr...

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Bibliographic Details
Published in:JAMA : the journal of the American Medical Association 2017-01, Vol.317 (4), p.355-356
Main Author: Komaroff, Anthony L
Format: Article
Language:English
Subjects:
Anastomosis, Roux-en-Y
Animals
Bacteroidetes - physiology
Diabetes
Diabetes Mellitus, Type 2 - microbiology
Energy Intake
Energy Metabolism - physiology
Firmicutes - physiology
Gastrointestinal Microbiome - genetics
Gastrointestinal Microbiome - physiology
Germ-Free Life - physiology
Humans
Mice
Obesity
Obesity - microbiology
Organisms
Polysaccharides - pharmacokinetics
Risk factors
Thinness - microbiology
Weight Loss
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Description
Summary:Obesity and type 2 diabetes mellitus are influenced both by genes and lifestyle. That is not news. However, the genes in the human microbiome also may play an important role, and that is news. It has been known for decades that gut bacteria synthesize essential vitamins and amino acids and help degrade toxins. During the past decade, it has become clear that the influence of the microbiome on health may be even more profound. Here, Komaroff talks about how microbiota affect obesity.
ISSN:0098-7484
1538-3598
DOI:10.1001/jama.2016.20099