Vasoplegic syndrome during Whipple procedure

Abstract Vasoplegic syndrome is an unusual cause of refractory hypotension under general anesthesia. It is commonly described in the setting of cardiac surgery, but rarely seen in noncardiac setting. We describe successful management of vasoplegic syndrome during Whipple procedure with vasopressin i...

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Bibliographic Details
Published in:Journal of clinical anesthesia 2017-02, Vol.36, p.151-152
Main Authors: Anandaswamy, Tejesh C., MD, Rajappa, Geetha C., DNB, Krishnamachar, Harish, MCh
Format: Article
Language:English
Subjects:
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Anesthesia
Anesthesia & Perioperative Care
Anesthesia, General - methods
Blood pressure
Cardiac arrhythmia
Diabetes
Dopamine
Heart rate
Heart surgery
Humans
Hypotension - drug therapy
Hypotension - etiology
Male
Nitric oxide
Noncardiac surgery
Pain Medicine
Pancreatic Neoplasms - surgery
Pancreaticoduodenectomy - adverse effects
Patients
Postoperative Care - methods
Risk factors
Smooth muscle
Vasoconstrictor Agents - therapeutic use
Vasoplegia - drug therapy
Vasoplegia - etiology
Vasoplegic syndrome
Vasopressin
Vasopressins - therapeutic use
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Summary:Abstract Vasoplegic syndrome is an unusual cause of refractory hypotension under general anesthesia. It is commonly described in the setting of cardiac surgery, but rarely seen in noncardiac setting. We describe successful management of vasoplegic syndrome during Whipple procedure with vasopressin infusion. A high index of suspicion and prompt treatment with vasopressin can be lifesaving in patients with risk factors for vasoplegic syndrome who present with severe refractory hypotension and who respond poorly to fluid administration and routine vasopressor infusion.
ISSN:0952-8180
1873-4529
DOI:10.1016/j.jclinane.2016.10.042