Is hand-grip another culprit for the risk of fractures in HIV-positive patients?

Risk of bone fractures in patients with HIV infection is greater than in the general population, particularly in those co-infected with hepatitis viruses. We compared bone mineral density (BMD) and muscular strength, measured by hand grip test (HG), in HIV mono-infected and co-infected patients. T-s...

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Bibliographic Details
Published in:The New microbiologica 2016-01, Vol.39 (1), p.61-64
Main Authors: Postorino, Maria Concetta, Torti, Carlo, Carè, Ilaria, Pisani, Vincenzo, Strazzulla, Alessio, Vaccaro, Vittoria, Costa, Chiara, Provenzano, Francesco, Mazzitelli, Maria, Pujia, Arturo, Montalcini, Tiziana
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Bone Density
Coinfection
Female
Fractures, Bone - etiology
Hand Injuries - etiology
Hand Strength
Hepatitis C - complications
HIV Infections - complications
Humans
Lentivirus
Male
Middle Aged
Retroviridae
Risk Factors
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Summary:Risk of bone fractures in patients with HIV infection is greater than in the general population, particularly in those co-infected with hepatitis viruses. We compared bone mineral density (BMD) and muscular strength, measured by hand grip test (HG), in HIV mono-infected and co-infected patients. T-score values were lower in HIV patients co-infected with hepatitis viruses vs. mono-infected individuals. Since no significant correlations between HG and T-scores were found, we hypothesize that these factors belong, at least in part, to independent pathways, so both should be taken into account as risks for fragility fractures. Larger prospective studies are needed to confirm this hypothesis.
ISSN:1121-7138