Effect of Reduced Renal Function on Time in Therapeutic Range Among Anticoagulated Atrial Fibrillation Patients

Atrial fibrillation (AF) patients with creatinine clearance below 30 ml/min have been excluded from randomized controlled trials of non-vitamin K antagonist oral anticoagulants, and the use of warfarin in this population is controversial. The logistic regression model was adjusted for females, >8...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American College of Cardiology 2017-02, Vol.69 (6), p.752-753
Main Authors: Bonde, Anders Nissen, MB, Lip, Gregory Y.H., MD, Kamper, Anne-Lise, MD, DMSc, Staerk, Laila, MD, Torp-Pedersen, Christian, MD, DMSc, Gislason, Gunnar Hilmar, MD, PhD, Olesen, Jonas Bjerring, MD, PhD
Format: Article
Language:English
Subjects:
Anticoagulants
Cardiology
Cardiovascular
Health risk assessment
Internal Medicine
Kidney diseases
Stroke
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Atrial fibrillation (AF) patients with creatinine clearance below 30 ml/min have been excluded from randomized controlled trials of non-vitamin K antagonist oral anticoagulants, and the use of warfarin in this population is controversial. The logistic regression model was adjusted for females, >80 years of age, with depression, diabetes, heart failure, hypertension, alcohol abuse, previous bleeding, and use of amiodarone and >=4 drugs at baseline.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2016.11.031