A red orange extract modulates the vascular response to a recreational dive: a pilot study on the effect of anthocyanins on the physiological consequences of scuba diving

Nutritional antioxidants have been proposed as an expedient strategy to counter the potentially deleterious effects of scuba diving on endothelial function, flow-mediated dilation (FMD) and heart function. Sixteen volunteers performing a single standard dive (20 min at 33 m) according to US Navy div...

Full description

Saved in:
Bibliographic Details
Published in:Natural product research 2016-09, Vol.30 (18), p.2101-2106
Main Authors: Balestra, C., Cimino, F., Theunissen, S., Snoeck, T., Provyn, S., Canali, R., Bonina, A., Virgili, F.
Format: Article
Language:English
Subjects:
Adult
anthocyanins
Anthocyanins - pharmacology
Antioxidants - pharmacology
Blood Vessels - drug effects
body water
Body Water - drug effects
Citrus sinensis - chemistry
Dietary Supplements
Diving
Diving - physiology
endothelial dysfunction
flow-mediated dilation
Hematocrit
Humans
Male
Pilot Projects
Plant Extracts - pharmacology
Vasodilation - drug effects
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Nutritional antioxidants have been proposed as an expedient strategy to counter the potentially deleterious effects of scuba diving on endothelial function, flow-mediated dilation (FMD) and heart function. Sixteen volunteers performing a single standard dive (20 min at 33 m) according to US Navy diving procedures were randomly assigned to two groups: one was administered with two doses of 200 mg of an anthocyanins (AC)-rich extract from red oranges, 12 and 4 h before diving. Anthocyanins supplementation significantly modulated the effects of diving on haematocrit, body water distribution and FMD. AC administration significantly reduces the potentially harmful endothelial effects of a recreational single dive. The lack of any significant effect on the most common markers of plasma antioxidant capacity suggests that the mechanism underlying this protective activity is independent of the putative antioxidant effect of AC and possibly involves cellular signalling modulation of the response to high oxygen.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2015.1107062