Meta-Analysis of Usefulness of Concomitant Mitral Valve Repair or Replacement for Moderate Ischemic Mitral Regurgitation With Coronary Artery Bypass Grafting

Moderate ischemic mitral regurgitation (MR) is often present in patients undergoing coronary artery bypass grafting (CABG). However, the clinical benefit of repairing moderate MR during CABG is unproven. We searched multiple databases to identify original studies comparing isolated CABG versus combi...

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Bibliographic Details
Published in:The American journal of cardiology 2017-03, Vol.119 (5), p.734-741
Main Authors: Altarabsheh, Salah E., MD, Deo, Salil V., MD, Dunlay, Shannon M., MD, Erwin, Patricia J., MD, Obeidat, Yagthan M., MD, Navale, Suparna, MS, Markowitz, Alan H., MD, Park, Soon J., MD
Format: Article
Language:English
Subjects:
Cardiovascular
Catheters
Clinical trials
Coronary Artery Bypass - methods
Coronary Artery Disease - surgery
Coronary vessels
Heart surgery
Humans
Meta-analysis
Methods
Mitral Valve Annuloplasty - methods
Mitral Valve Insufficiency - etiology
Mitral Valve Insufficiency - surgery
Mortality
Myocardial Ischemia - complications
Proportional Hazards Models
Severity of Illness Index
Studies
Survival Rate
Veins & arteries
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Summary:Moderate ischemic mitral regurgitation (MR) is often present in patients undergoing coronary artery bypass grafting (CABG). However, the clinical benefit of repairing moderate MR during CABG is unproven. We searched multiple databases to identify original studies comparing isolated CABG versus combined CABG and MR surgery (mitral valve surgery with coronary artery bypass grafting [MVCABG]); survival (either early or midterm) was the primary end point. Risk ratio (RR) or standardize mean difference was selected as the effect estimates; survival was compared by pooling hazard ratios. All results are presented with 95% CIs; p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2016.11.024