Serum cytokine/chemokine profiles in patients with dengue fever (DF) and dengue hemorrhagic fever (FHD) by using protein array

Highlights • Early prediction of dengue disease severity is important to prevent mortality. • The aim of this study was to find potential prognostic markers of dengue severity. • Serum expression levels of 36 cytokines were determined in DF and DHF patients. • Differences were found in GRO-α and IP-...

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Bibliographic Details
Published in:Journal of clinical virology 2017-04, Vol.89, p.39-45
Main Authors: dos Santos Oliveira, Renato Antonio, Cordeiro, Marli Tenório, de Moura, Patrícia Muniz Mendes Freire, Filho, Paulo Neves Baptista, de Mendonça Braga-Neto, Ulisses, de Azevedo Marques, Ernesto Torres, Vega Gonzales Gil, Laura Helena
Format: Article
Language:English
Subjects:
Adolescent
Adult
Allergy and Immunology
Biomarkers - blood
Cytokines - blood
Cytokines protein array
Dengue - pathology
Dengue fever
Dengue hemorrhagic fever
Female
Humans
Infectious Disease
Male
Prognosis
Prognostic marker
Protein Array Analysis
Serum - chemistry
Volunteers
Young Adult
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Summary:Highlights • Early prediction of dengue disease severity is important to prevent mortality. • The aim of this study was to find potential prognostic markers of dengue severity. • Serum expression levels of 36 cytokines were determined in DF and DHF patients. • Differences were found in GRO-α and IP-10 expression levels during the acute phase.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2017.02.007