Wireless electrostimulation: a new approach in combating infection?

Electrostimulation (ES), hitherto successfully employed in wound treatment, has shown potential in antimicrobial applications, suggesting its use as synergistic to or replacement of antibiotics. The differential susceptibility of pathogens and host tissue and organs to various ES modalities might al...

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Bibliographic Details
Published in:Future microbiology 2017-03, Vol.12 (3), p.255-265
Main Authors: Kambouris, Manousos E, Markogiannakis, Antonios, Arabatzis, Michael, Manoussopoulos, Yiannis, Kantzanou, Maria, Velegraki, Aristea
Format: Article
Language:English
Subjects:
20th century
Antibiotics
Bacteria
Bacteria - radiation effects
Bacterial Infections - microbiology
Bacterial Infections - therapy
Bioelectricity
Chemical compounds
Electric Stimulation Therapy
electroceuticals
Electrocutions
Electrodes
Electromagnetism
electrostimulation
electrotherapy
environmental footprint
expeditionary medicine
Health risks
Humans
Infections
Negative selection
noncontact current transfer
Organs
Pathogens
resistance in antibiotics
sustainability in treatment
Transcutaneous Electric Nerve Stimulation
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Summary:Electrostimulation (ES), hitherto successfully employed in wound treatment, has shown potential in antimicrobial applications, suggesting its use as synergistic to or replacement of antibiotics. The differential susceptibility of pathogens and host tissue and organs to various ES modalities might allow selective use against specific infections. The use of ES is cheaper in terms of development/testing, routine application and environmental footprint. If extensive substitution of chemical compounds is achieved, the development of resistance might be reversed through negative selection. A promising setup of ES seems to be the noncontact current transfer, due to low amperage similar to innate bioelectricity, painlessness, simple logistics and low risk for treatment-caused infection.
ISSN:1746-0913
1746-0921
DOI:10.2217/fmb-2017-0157