Perilesional edema in brain metastasis from non-small cell lung cancer (NSCLC) as predictor of response to radiosurgery (SRS)

Radiosurgery (SRS) is widely used in the treatment of brain oligo-metastases from NSCLC. The aim of present study is to evaluate the extent of perilesional edema in brain metastases as predictive factor of treatment response. This single center retrospective study included 42 consecutive patients (J...

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Bibliographic Details
Published in:Neurological sciences 2017-06, Vol.38 (6), p.975-982
Main Authors: Tini, Paolo, Nardone, Valerio, Pastina, Pierpaolo, Battaglia, Giuseppe, Vinciguerra, Claudia, Carfagno, Tommaso, Rubino, Giovanni, Carbone, Salvatore Francesco, Sebaste, Lucio, Cerase, Alfonso, Federico, Antonio, Pirtoli, Luigi
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Brain - diagnostic imaging
Brain - radiation effects
Brain - surgery
Brain cancer
Brain Edema - diagnostic imaging
Brain Edema - etiology
Brain Edema - therapy
Brain Neoplasms - complications
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - secondary
Brain Neoplasms - therapy
Carcinoma, Non-Small-Cell Lung - pathology
Carcinoma, Non-Small-Cell Lung - therapy
Disease Progression
Disease-Free Survival
Edema
Female
Follow-Up Studies
Humans
Kaplan-Meier Estimate
Lung cancer
Lungs
Magnetic Resonance Imaging
Male
Medicine
Medicine & Public Health
Metastases
Metastasis
Middle Aged
Neoplasm Recurrence, Local
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Non-small cell lung carcinoma
Original Article
Prognosis
Psychiatry
Radiosurgery
Retrospective Studies
Severity of Illness Index
Survival
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Description
Summary:Radiosurgery (SRS) is widely used in the treatment of brain oligo-metastases from NSCLC. The aim of present study is to evaluate the extent of perilesional edema in brain metastases as predictive factor of treatment response. This single center retrospective study included 42 consecutive patients (January 2011–December 2014) with 1–2 brain metastasis from NSCLC treated with Radiosurgery (SRS). Extent of perilesional edema was measured as maximal extension from the edge of lesion and classified as minor (
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-017-2876-y